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Singh S, Singh S, Tiwari MB, et al. Microflora analysis in the postchemotherapy patients of oral cancer. Natl J Maxillofac Surg. 2019;10(2):141-145doi: 10.4103/njms.NJMS_7_19.
Singh, S., Singh, S., Tiwari, M. B., Pal, U. S., & Kumar, S. (2019). Microflora analysis in the postchemotherapy patients of oral cancer. National journal of maxillofacial surgery, 10(2), 141-145. https://doi.org/10.4103/njms.NJMS_7_19
Singh, Sunita, et al. "Microflora analysis in the postchemotherapy patients of oral cancer." National journal of maxillofacial surgery vol. 10,2 (2019): 141-145. doi: https://doi.org/10.4103/njms.NJMS_7_19
Singh S, Singh S, Tiwari MB, Pal US, Kumar S. Microflora analysis in the postchemotherapy patients of oral cancer. Natl J Maxillofac Surg. 2019 Jul-Dec;10(2):141-145. doi: 10.4103/njms.NJMS_7_19. Epub 2019 Nov 12. PMID: 31798247; PMCID: PMC6883871.
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Natl J Maxillofac Surg. 2019 Jul-Dec;10(2):141-145. doi: 10.4103/njms.NJMS_7_19. Epub 2019 Nov 12.

Microflora analysis in the postchemotherapy patients of oral cancer.

National journal of maxillofacial surgery

Sunita Singh, Seema Singh, M B Tiwari, U S Pal, Santosh Kumar

Affiliations

  1. Department of Microbiology, King Georges Medical University, Lucknow, Uttar Pradesh, India.
  2. Department of Respiratory Medicine, King Georges Medical University, Lucknow, Uttar Pradesh, India.
  3. Department of Oral and Maxillofacial Surgery, King Georges Medical University, Lucknow, Uttar Pradesh, India.

PMID: 31798247 PMCID: PMC6883871 DOI: 10.4103/njms.NJMS_7_19

Abstract

BACKGROUND: To assess changes in oral microflora in dental plaque from cancer patients within 7 days of the first course of chemotherapy and the relationship of the changes with mucositis.

MATERIALS AND METHODS: Thirty cancer patients, divided into a test group undergoing chemotherapy and a control group not undergoing chemotherapy, were enrolled in this pilot study. Oral microflora was cultured from three samples of dental plaque at t0 (before chemotherapy), t1 (1 day after chemotherapy), and t2 (7 days after chemotherapy). Single and crossed descriptive analyses were used to establish prevalence, and the Chi-square test was used to establish the statistical significance of the differences observed in distributions (significance level:

RESULTS: In most patients (55%), oral microflora consisted mainly of Gram-positive cocci, while the remaining 45% of the bacterial flora also had periodontal-pathogenic species. No

CONCLUSIONS: The results of this pilot study indicate that there were no changes in microflora in dental plaque in cancer patients within 7 days of the first course of chemotherapy. No correlations between oral mucositis and specific microorganisms were assessed.

Copyright: © 2019 National Journal of Maxillofacial Surgery.

Keywords: Cancer patients; chemotherapy; dental plaque; oral microflora

Conflict of interest statement

There are no conflicts of interest.

References

  1. J Bacteriol. 2001 Jun;183(12):3770-83 - PubMed
  2. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jan;103(1):48-59 - PubMed
  3. Photomed Laser Surg. 2014 Feb;32(2):81-7 - PubMed
  4. Clin Oral Investig. 2012 Dec;16(6):1579-88 - PubMed
  5. Support Care Cancer. 2000 Sep;8(5):366-71 - PubMed
  6. J Clin Periodontol. 2009 Oct;36(10):823-9 - PubMed
  7. SADJ. 2010 Sep;65(8):372-4 - PubMed
  8. J Clin Microbiol. 1992 Oct;30(10):2657-61 - PubMed
  9. Oral Dis. 2015 Jan;21(1):17-30 - PubMed
  10. J Clin Periodontol. 1991 Jul;18(6):411-20 - PubMed
  11. Cochrane Database Syst Rev. 2010 Aug 04;(8):CD001973 - PubMed
  12. Med Oral Patol Oral Cir Bucal. 2011 Nov 01;16(7):e1036-42 - PubMed
  13. Arch Microbiol. 2013 Jun;195(6):371-83 - PubMed
  14. Int J Oral Sci. 2011 Oct;3(4):209-15 - PubMed
  15. Support Care Cancer. 2012 Dec;20(12):3231-40 - PubMed
  16. J Clin Microbiol. 1992 Jun;30(6):1462-8 - PubMed
  17. Oral Oncol. 1998 Nov;34(6):476-83 - PubMed
  18. Acta Clin Belg. 1993;48(2):81-5 - PubMed
  19. Cell Host Microbe. 2013 Aug 14;14(2):207-15 - PubMed
  20. Dent Clin North Am. 2003 Oct;47(4):709-31, vii - PubMed
  21. J Clin Microbiol. 2009 Jan;47(1):235-8 - PubMed
  22. Periodontol 2000. 2010 Feb;52(1):12-37 - PubMed

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