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Sansalone L, Zhao J, Richers MT, et al. Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission. Beilstein J Org Chem. 2019;15:2812-2821doi: 10.3762/bjoc.15.274.
Sansalone, L., Zhao, J., Richers, M. T., & Ellis-Davies, G. C. R. (2019). Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission. Beilstein journal of organic chemistry, 152812-2821. https://doi.org/10.3762/bjoc.15.274
Sansalone, Lorenzo, et al. "Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission." Beilstein journal of organic chemistry vol. 15 (2019): 2812-2821. doi: https://doi.org/10.3762/bjoc.15.274
Sansalone L, Zhao J, Richers MT, Ellis-Davies GCR. Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission. Beilstein J Org Chem. 2019 Nov 21;15:2812-2821. doi: 10.3762/bjoc.15.274. eCollection 2019. PMID: 31807216; PMCID: PMC6880823.
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Beilstein J Org Chem. 2019 Nov 21;15:2812-2821. doi: 10.3762/bjoc.15.274. eCollection 2019.

Chemical tuning of photoswitchable azobenzenes: a photopharmacological case study using nicotinic transmission.

Beilstein journal of organic chemistry

Lorenzo Sansalone, Jun Zhao, Matthew T Richers, Graham C R Ellis-Davies

Affiliations

  1. Department of Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA.

PMID: 31807216 PMCID: PMC6880823 DOI: 10.3762/bjoc.15.274

Abstract

We have developed photochromic probes for the nicotinic acetylcholine receptor that exploit the unique chemical properties of the tetrafluoroazobenzene (4FAB) scaffold. Ultraviolet light switching and rapid thermal relaxation of the metastable

Copyright © 2019, Sansalone et al.; licensee Beilstein-Institut.

Keywords: acetylcholine receptors; bidirectional; photoswitchable drug; tetrafluoroazobenzene; visible light

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