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Anal Chem. 2020 Jan 21;92(2):2112-2120. doi: 10.1021/acs.analchem.9b04633. Epub 2020 Jan 02.

Portable NMR with Parallelism.

Analytical chemistry

Ka-Meng Lei, Dongwan Ha, Yi-Qiao Song, Robert M Westervelt, Rui Martins, Pui-In Mak, Donhee Ham

Affiliations

  1. State Key Laboratory of Analog and Mixed-Signal VLSI , University of Macau , Macau , P. R. China.
  2. John A. Paulson School of Engineering and Applied Sciences , Harvard University , Cambridge , Massachusetts 02138 , United States.
  3. Schlumberger-Doll Research Center , Cambridge , Massachusetts 02139 , United States.
  4. Department of Physics , Harvard University , Cambridge , Massachusetts 02138 , United States.
  5. Instituto Superior Técnico , Universidade de Lisboa , Lisbon 1049-001 , Portugal.

PMID: 31894967 DOI: 10.1021/acs.analchem.9b04633

Abstract

Portable NMR combining a permanent magnet and a complementary metal-oxide-semiconductor (CMOS) integrated circuit has recently emerged to offer the long desired online, on-demand, or in situ NMR analysis of small molecules for chemistry and biology. Here we take this cutting-edge technology to the next level by introducing parallelism to a state-of-the-art portable NMR platform to accelerate its experimental throughput, where NMR is notorious for inherently low throughput. With multiple (

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