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Perdomo SJ, Gibbs BB, Kowalsky RJ, et al. Effects of Alternating Standing and Sitting Compared to Prolonged Sitting on Cerebrovascular Hemodynamics. Sport Sci Health. 2019;15(2):375-383doi: 10.1007/s11332-019-00526-4.
Perdomo, S. J., Gibbs, B. B., Kowalsky, R. J., Taormina, J. M., & Balzer, J. R. (2019). Effects of Alternating Standing and Sitting Compared to Prolonged Sitting on Cerebrovascular Hemodynamics. Sport sciences for health, 15(2), 375-383. https://doi.org/10.1007/s11332-019-00526-4
Perdomo, Sophy J, et al. "Effects of Alternating Standing and Sitting Compared to Prolonged Sitting on Cerebrovascular Hemodynamics." Sport sciences for health vol. 15,2 (2019): 375-383. doi: https://doi.org/10.1007/s11332-019-00526-4
Perdomo SJ, Gibbs BB, Kowalsky RJ, Taormina JM, Balzer JR. Effects of Alternating Standing and Sitting Compared to Prolonged Sitting on Cerebrovascular Hemodynamics. Sport Sci Health. 2019 Aug;15(2):375-383. doi: 10.1007/s11332-019-00526-4. Epub 2019 Jan 23. PMID: 31814853; PMCID: PMC6897374.
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Sport Sci Health. 2019 Aug;15(2):375-383. doi: 10.1007/s11332-019-00526-4. Epub 2019 Jan 23.

Effects of Alternating Standing and Sitting Compared to Prolonged Sitting on Cerebrovascular Hemodynamics.

Sport sciences for health

Sophy J Perdomo, Bethany Barone Gibbs, Robert J Kowalsky, John M Taormina, Jeffrey R Balzer

Affiliations

  1. Department of Health and Physical Activity, University of Pittsburgh, Pittsburgh, PA.
  2. Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, KS.
  3. Department of Health and Kinesiology, Texas A&M University-Kingsville, Kingsville, TX.
  4. Neurological Surgery, University of Pittsburgh, Pittsburgh, PA.

PMID: 31814853 PMCID: PMC6897374 DOI: 10.1007/s11332-019-00526-4

Abstract

PURPOSE: Previous research suggests that prolonged sitting may acutely reduce cerebral blood flow velocity (CBFv). The purpose of this study was to evaluate the effects of alternating standing and sitting vs prolonged sitting on CBFv.

METHODS: This randomized crossover study enrolled working adults (N=25) with pre-to-stage 1 hypertension not using antihypertensive medications, and a body mass index from 25 to < 40 kg/m

RESULTS: Mean±SD age was 42±12 years, blood pressure (BP) was 132±9/83±8 mmHg, and BMI was 32±5 kg/m

CONCLUSIONS: In individuals with elevated BP and BMI, CBFv significantly decreased by midday and increased by afternoon, especially during a workday of prolonged sitting. Future studies should evaluate the combination of frequent walks and a sit-stand desk to break up prolonged sitting.

Keywords: cerebrovascular hemodynamics; sedentary behaviour; sit-stand desk; transcranial Doppler

Conflict of interest statement

Conflict of Interest Dr. Gibbs discloses funding from Humanscale. Drs. Perdomo, Kowalsky, Balzer and Mr. Taormina disclose no conflicts of interest.

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