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Heliyon. 2019 Nov 14;5(11):e02802. doi: 10.1016/j.heliyon.2019.e02802. eCollection 2019 Nov.

Effect of an antimicrobial drug on lung microbiota in healthy dogs.

Heliyon

Aline Fastrès, Bernard Taminiau, Emilie Vangrinsven, Alexandru-Cosmin Tutunaru, Evelyne Moyse, Frederic Farnir, Georges Daube, Cécile Clercx

Affiliations

  1. Department of Clinical Sciences, FARAH, Faculty of Veterinary Medicine, University of Liège, 4000, Liège, Belgium.
  2. Department of Food Sciences - Microbiology, FARAH, Faculty of Veterinary Medicine, University of Liège, 4000, Liège, Belgium.
  3. Department of Veterinary Management of Animal Resources, FARAH, Faculty of Veterinary Medicine, University of Liège, 4000, Liège, Belgium.

PMID: 31844730 PMCID: PMC6895694 DOI: 10.1016/j.heliyon.2019.e02802

Abstract

Alterations of the lung microbiota (LM) are associated with clinical features in chronic lung diseases (CLDs) with growing evidence that an altered LM contributes to the pathogenesis of such disorders. The common use of antimicrobial drugs in the management of CLDs likely represents a confounding factor in the study of the LM. The aim of the present study was to assess the effect of oral administration of amoxicillin/clavulanic acid (AC) on the LM in healthy dogs (

© 2019 The Author(s).

Keywords: Antimicrobial; Antimicrobial drug; Bacteriology; Clinical research; Dog; Health sciences; Lung microbiota; Microbiology; Respiratory system; Veterinary medicine; Zoology

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