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Faron M, Corte H, Poghosyan T, et al. Quality of Life After Caustic Ingestion. Ann Surg. 2021;274(6):e529-e534doi: 10.1097/SLA.0000000000003774.
Faron, M., Corte, H., Poghosyan, T., Bruzzi, M., Voron, T., Sarfati, E., Cattan, P., & Chirica, M. (2021). Quality of Life After Caustic Ingestion. Annals of surgery, 274(6), e529-e534. https://doi.org/10.1097/SLA.0000000000003774
Faron, Matthieu, et al. "Quality of Life After Caustic Ingestion." Annals of surgery vol. 274,6 (2021): e529-e534. doi: https://doi.org/10.1097/SLA.0000000000003774
Faron M, Corte H, Poghosyan T, Bruzzi M, Voron T, Sarfati E, Cattan P, Chirica M. Quality of Life After Caustic Ingestion. Ann Surg. 2021 Dec 01;274(6):e529-e534. doi: 10.1097/SLA.0000000000003774. PMID: 31972647.
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Ann Surg. 2021 Dec 01;274(6):e529-e534. doi: 10.1097/SLA.0000000000003774.

Quality of Life After Caustic Ingestion.

Annals of surgery

Matthieu Faron, Helene Corte, Tigran Poghosyan, Matthieu Bruzzi, Thibault Voron, Emile Sarfati, Pierre Cattan, Mircea Chirica

Affiliations

  1. Department of Digestive and Endocrine Surgery, Saint-Louis Hospital AP-HP, Université Paris Diderot Sorbonne Paris Cité, Paris, France.
  2. Department of Biostatistics and Epidemiology, Inserm UNIT 1018 CESP Oncostat Team, Gustave Roussy Cancer Campus, Villejuif, France.
  3. Department of Digestive and Emergency Surgery, University Hospital of Grenoble, Grenoble Alpes University, Grenoble, France.

PMID: 31972647 DOI: 10.1097/SLA.0000000000003774

Abstract

OBJECTIVE: The aim of the study was to evaluate long-term QOL after caustic ingestion.

BACKGROUND: Caustic ingestion strongly affects patient's QOL but data on the topic is scarce in the literature.

METHODS: QOL evaluation was conducted in survivors from a large cohort of patients with caustic injuries. QOL was assessed using the EORTC QLQ-OG25 module, the SF12v2 score, and the hospital anxiety and depression scale questionnaire. One hundred thirty-four patients (59 men, median age 43) completed the survey; 72 (54%) patients underwent emergency digestive resection and in 99 (74%) patients underwent esophageal reconstruction. Results of QOL questionnaires were compared to average values determined in healthy volunteers and in patients with esophageal cancers.

RESULTS: The median QLQ-OG25 score was 44 (34, 62) and values were significantly lower when compared to a normal population (P < 0.0001). SF12v2 scores were significantly inferior to those expected in a normal population on both the physical component summary (PCS) (43.3 ± 10.8; P < 0.0001) and the mental component summary (44 ± 9.7; P < 0.0001) scales. Emergency esophageal resection was significantly associated with higher QLQ-OG25 scores (P < 0.0001), but not with mental component summary (P = 0.3), PCS (P = 0.76), HAD anxiety (P = 0.95), and HAD depression scores (P = 0.59); results were similar after extended emergency resection. When compared to esophagocoloplasty alone, pharyngeal reconstruction had a significant negative impact on QLQ-OG25 (P < 0.0001), PCS (P = 0.01), and HAD depression (P = 0.0008) scores.

CONCLUSIONS: QOL is significantly impaired after caustic ingestion. QOL issues should not influence the emergency surgical strategy but deserve discussion before esophageal reconstruction for caustic injuries.

Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.

Conflict of interest statement

The authors report no conflicts of interest.

References

  1. Chirica M, Bonavina L, Kelly MD, et al. Caustic ingestion. Lancet 2017; 389:2041–2052. - PubMed
  2. Chirica M, Brette MD, Faron M, et al. Upper digestive tract reconstruction for caustic injuries. Ann Surg 2015; 261:894–901. - PubMed
  3. Contini S, Scarpignato C. Caustic injury of the upper gastrointestinal tract: a comprehensive review. World J Gastroenterol 2013; 19:3918–3930. - PubMed
  4. Raynaud K, Seguy D, Rogosnitzky M, et al. Conservative management of severe caustic injuries during acute phase leads to superior long-term nutritional and quality of life (QoL) outcome. Langenbecks Arch Surg 2015; 401:81–87. - PubMed
  5. Chirica M, Resche-Rigon M, Zagdanski AM, et al. Computed tomography evaluation of esophagogastric necrosis after caustic ingestion. Ann Surg 2016; 264:107–113. - PubMed
  6. Zargar SA, Kochhar R, Nagi B, et al. Ingestion of corrosive acids. Spectrum of injury to upper gastrointestinal tract and natural history. Gastroenterology 1989; 97:702–707. - PubMed
  7. Chirica M, Resche-Rigon M, Bongrand NM, et al. Surgery for caustic injuries of the upper gastrointestinal tract. Ann Surg 2012; 256:994–1001. - PubMed
  8. Chirica M, Resche-Rigon M, Pariente B, et al. Computed tomography evaluation of high-grade esophageal necrosis after corrosive ingestion to avoid unnecessary esophagectomy. Surg Endosc 2015; 29:1452–1461. - PubMed
  9. Chirica M, Veyrie N, Munoz-Bongrand N, et al. Late morbidity after colon interposition for corrosive esophageal injury: risk factors, management, and outcome. A 20-years experience. Ann Surg 2010; 252:271–280. - PubMed
  10. Chirica M, de Chaisemartin C, Goasguen N, et al. Colopharyngoplasty for the treatment of severe pharyngoesophageal caustic injuries: an audit of 58 patients. Ann Surg 2007; 246:721–727. - PubMed
  11. Lagergren P, Fayers P, Conroy T, et al. Clinical and psychometric validation of a questionnaire module, the EORTC QLQ-OG25, to assess health-related quality of life in patients with cancer of the oesophagus, the oesophago-gastric junction and the stomach. Eur J Cancer 2007; 43:2066–2073. - PubMed
  12. Available at: http://www.sf-36.org/demos/SF-12v2.html Accessed October 31, 2019. - PubMed
  13. Snaith RP. The hospital anxiety and depression scale. Health Qual Life Outcomes 2003; 1:29–32. - PubMed
  14. van der Schaaf M, Derogar M, Lagergren P. Reference values of oesophago-gastric symptoms (EORTC QLQ-OG25) in a population-based setting. Eur J Cancer 2012; 48:1602–1607. - PubMed

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