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Zhou Z, Kinslow CJ, Wang P, et al. Clear Cell Adenocarcinoma of the Urinary Bladder Is a Glycogen-Rich Tumor with Poorer Prognosis. J Clin Med. 2020;9(1)doi: 10.3390/jcm9010138.
Zhou, Z., Kinslow, C. J., Wang, P., Huang, B., Cheng, S. K., Deutsch, I., Gentry, M. S., & Sun, R. C. (2020). Clear Cell Adenocarcinoma of the Urinary Bladder Is a Glycogen-Rich Tumor with Poorer Prognosis. Journal of clinical medicine, 9(1), . https://doi.org/10.3390/jcm9010138
Zhou, Zhengqiu, et al. "Clear Cell Adenocarcinoma of the Urinary Bladder Is a Glycogen-Rich Tumor with Poorer Prognosis." Journal of clinical medicine vol. 9,1 (2020). doi: https://doi.org/10.3390/jcm9010138
Zhou Z, Kinslow CJ, Wang P, Huang B, Cheng SK, Deutsch I, Gentry MS, Sun RC. Clear Cell Adenocarcinoma of the Urinary Bladder Is a Glycogen-Rich Tumor with Poorer Prognosis. J Clin Med. 2020 Jan 03;9(1). doi: 10.3390/jcm9010138. PMID: 31947882; PMCID: PMC7019566.
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J Clin Med. 2020 Jan 03;9(1). doi: 10.3390/jcm9010138.

Clear Cell Adenocarcinoma of the Urinary Bladder Is a Glycogen-Rich Tumor with Poorer Prognosis.

Journal of clinical medicine

Zhengqiu Zhou, Connor J Kinslow, Peng Wang, Bin Huang, Simon K Cheng, Israel Deutsch, Matthew S Gentry, Ramon C Sun

Affiliations

  1. Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY 40536, USA.
  2. Department of Radiation Oncology, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
  3. Division of Medical Oncology, Department of Internal Medicine, College of Medicine, University of Kentucky, Lexington, KY 40536, USA.
  4. Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY 40536, USA.
  5. Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY 10032, USA.
  6. Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.
  7. Department of Neuroscience, University of Kentucky College of Medicine, Lexington, KY 40536, USA.

PMID: 31947882 PMCID: PMC7019566 DOI: 10.3390/jcm9010138

Abstract

Clear cell adenocarcinoma (CCA) is a rare variant of urinary bladder carcinoma with a glycogen-rich phenotype and unknown prognosis. Using the National Cancer Institute's surveillance, epidemiology, and end results (SEER) program database, we documented recent trends in incidence, mortality, demographical characteristics, and survival on this rare subtype of urinary bladder cancer. The overall age-adjusted incidence and mortality of CCA was 0.087 (95% confidence interval (CI): 0.069-0.107) and 0.064 (95% CI: 0.049-0.081) respectively per million population. In comparison to non-CCAs, CCAs were more commonly associated with younger age (<60 years old,

Keywords: SEER program database; clear-cell adenocarcinoma; glycogen; urinary bladder

Conflict of interest statement

The authors declare no conflict of interest. Cheng reports personal fees and non-financial support from AbbVie and Sanofi. Gentry and Sun report personal fees and non-financial support from Maze Thera

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