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Intelligence. 2020 Jan-Feb;78:101407. doi: 10.1016/j.intell.2019.101407.

Fluctuating asymmetry in brain structure and general intelligence in 73-year-olds.

Intelligence

Joanna E Moodie, Stuart J Ritchie, Simon R Cox, Mathew A Harris, Susana Muñoz Maniega, Maria C Valdés Hernández, Alison Pattie, Janie Corley, Mark E Bastin, John M Starr, Joanna M Wardlaw, Ian J Deary

Affiliations

  1. School of Psychology and Neuroscience, St Andrews University, St Andrews, UK.
  2. Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, UK.
  3. Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.
  4. Department of Psychology, The University of Edinburgh, Edinburgh, UK.
  5. Scottish Imaging Network, A Platform for Scientific Excellence (SINAPSE) Collaboration, Edinburgh, UK.
  6. Division of Psychiatry, The University of Edinburgh, Edinburgh, UK.
  7. Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, UK.
  8. Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, UK.

PMID: 31983789 PMCID: PMC6961972 DOI: 10.1016/j.intell.2019.101407

Abstract

Fluctuating body asymmetry is theorized to indicate developmental instability, and to have small positive associations with low socioeconomic status (SES). Previous studies have reported small negative associations between fluctuating body asymmetry and cognitive functioning, but relationships between fluctuating brain asymmetry and cognitive functioning remain unclear. The present study investigated the association between general intelligence (a latent factor derived from a factor analysis on 13 cognitive tests) and the fluctuating asymmetry of four structural measures of brain hemispheric asymmetry: cortical surface area, cortical volume, cortical thickness, and white matter fractional anisotropy. The sample comprised members of the Lothian Birth Cohort 1936 (LBC1936,

© 2019 The Authors.

Keywords: Cortical asymmetry; Fluctuating asymmetry; Fractional anisotropy; Intelligence; P-FIT

References

  1. Mol Autism. 2016 May 24;7:28 - PubMed
  2. Pediatr Res. 2007 Nov;62(5):636-42 - PubMed
  3. Trends Cogn Sci. 2009 Feb;13(2):65-73 - PubMed
  4. J Neurosci. 2014 Apr 30;34(18):6294-302 - PubMed
  5. Psychol Aging. 2009 Dec;24(4):792-808 - PubMed
  6. Schizophr Res. 2007 Jul;93(1-3):66-78 - PubMed
  7. PLoS One. 2009 Sep 29;4(9):e7200 - PubMed
  8. Neuroimage. 2018 Apr 15;170:249-256 - PubMed
  9. Proc Biol Sci. 1997 Jun 22;264(1383):823-9 - PubMed
  10. Dev Psychol. 2015 Apr;51(4):524-32 - PubMed
  11. Pediatrics. 2015 Feb;135(2):e440-8 - PubMed
  12. Child Dev Perspect. 2010 Apr 1;4(1):10-18 - PubMed
  13. J Epidemiol Community Health. 2001 Jan;55(1):10-5 - PubMed
  14. Cereb Cortex. 2009 Nov;19(11):2728-35 - PubMed
  15. Int J Stroke. 2011 Dec;6(6):547-59 - PubMed
  16. Int J Epidemiol. 2012 Dec;41(6):1576-84 - PubMed
  17. J Neurosci. 2015 Jun 3;35(22):8672-82 - PubMed
  18. Mol Psychiatry. 2012 Oct;17(10):1026-30 - PubMed
  19. Neuroimage. 2004 Aug;22(4):1466-79 - PubMed
  20. Neuroimage. 2010 Oct 1;52(4):1215-23 - PubMed
  21. Am J Med Genet. 1996 Dec 2;66(1):15-20 - PubMed
  22. Econ Hum Biol. 2013 Mar;11(2):236-44 - PubMed
  23. Intelligence. 2016 Nov-Dec;59:115-126 - PubMed
  24. Front Psychol. 2011 Feb 09;2:1 - PubMed
  25. Dev Psychol. 2004 Sep;40(5):805-12 - PubMed
  26. Neuroimage. 2007 Jan 1;34(1):144-55 - PubMed
  27. BMC Geriatr. 2007 Dec 05;7:28 - PubMed
  28. Early Hum Dev. 2013 Aug;89(8):531-5 - PubMed
  29. Neuroimage. 2006 Jul 1;31(3):968-80 - PubMed
  30. Neuropsychologia. 2012 Jul;50(9):2212-23 - PubMed
  31. Behav Brain Sci. 2007 Apr;30(2):135-54; discussion 154-87 - PubMed
  32. Front Aging Neurosci. 2016 Jan 19;7:250 - PubMed
  33. Neuroimage. 2004;23 Suppl 1:S208-19 - PubMed
  34. Brain Struct Funct. 2018 Jan;223(1):509-518 - PubMed
  35. Brain Struct Funct. 2014 Jan;219(1):1-22 - PubMed
  36. Am J Hum Biol. 2010 Jul-Aug;22(4):557-62 - PubMed
  37. Hum Brain Mapp. 2014 Dec;35(12):6011-22 - PubMed
  38. J Evol Biol. 2006 Nov;19(6):1727-43 - PubMed
  39. Hum Brain Mapp. 2009 Nov;30(11):3563-73 - PubMed
  40. Neurobiol Aging. 2009 Mar;30(3):432-40 - PubMed
  41. Neuroimage. 2010 May 15;51(1):1-10 - PubMed
  42. Psychiatry Res. 2012 Jan 30;201(1):48-53 - PubMed
  43. Int J Epidemiol. 2018 Aug 1;47(4):1042-1042r - PubMed
  44. Nature. 2016 Aug 11;536(7615):171-178 - PubMed

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