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BJGP Open. 2020 May 01;4(1). doi: 10.3399/bjgpopen20X101010. Print 2020.

Cannabidiol prescription in clinical practice: an audit on the first 400 patients in New Zealand.

BJGP open

Graham Gulbransen, William Xu, Bruce Arroll

Affiliations

  1. Private Practitioner, Cannabis Care NZ, West Care Specialist Centre, Auckland, New Zealand [email protected].
  2. Medical Student, Department of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.
  3. Professor and Head of Department, Department of General Practice and Primary Health Care, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.

PMID: 32019776 PMCID: PMC7330185 DOI: 10.3399/bjgpopen20X101010

Abstract

BACKGROUND: Cannabidiol (CBD) is the non-euphoriant component of cannabis. In 2017, the New Zealand Misuse of Drugs Regulations (1977) were amended, allowing doctors to prescribe CBD. Therapeutic benefit and tolerability of CBD remains unclear.

AIM: To review the changes in self-reported quality of life measurements, drug tolerability, and dose-dependent relationships in patients prescribed CBD oil for various conditions at a single institution.

DESIGN & SETTING: An audit including all patients (

RESULTS: Four hundred patients were assessed for CBD and 397 received a prescription. Follow-up was completed on 253 patients (63.3%). Patients reported a mean increase of 13.6 points (

CONCLUSION: There may be analgesic and anxiolytic benefits of CBD in patients with non-cancer chronic pain and mental health conditions such as anxiety. CBD is well tolerated, making it safe to trial for non-cancer chronic pain, mental health, neurological, and cancer symptoms.

Copyright © 2020, The Authors.

Keywords: analgesics; anti-anxiety agents; cannabidiol; cannabis; chronic pain; community care; depression; mental health; patient reported outcome measures; prescribing; therapy in mental health

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