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J Nucl Cardiol. 2020 Feb 05; doi: 10.1007/s12350-020-02046-y. Epub 2020 Feb 05.

Imaging inflammation in atherosclerotic plaques, targeting SST.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology

Eric J Meester, Boudewijn J Krenning, Erik de Blois, Marion de Jong, Antonius F W van der Steen, Monique R Bernsen, Kim van der Heiden

Affiliations

  1. Department of Biomedical Engineering, Thorax Center, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.
  2. Department of Radiology & Nuclear Medicine, Erasmus MC, Rotterdam, The Netherlands.
  3. Department of Cardiology, Thorax Center, Erasmus MC, Rotterdam, The Netherlands.
  4. Department of Biomedical Engineering, Thorax Center, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. [email protected].

PMID: 32026330 DOI: 10.1007/s12350-020-02046-y

Abstract

BACKGROUND: Imaging Somatostatin Subtype Receptor 2 (SST

METHODS AND RESULTS: Atherosclerotic ApoE

CONCLUSIONS: The results of this study indicate DOTA-JR11 as a promising ligand for visualization of atherosclerotic plaque inflammation.

Keywords: SPECT; atherosclerosis; inflammation; molecular imaging

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