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Oncotarget. 2020 Jan 07;11(1):1-14. doi: 10.18632/oncotarget.27338. eCollection 2020 Jan 07.

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative.

Oncotarget

Elena Fountzilas, Vassiliki Kotoula, Georgia-Angeliki Koliou, Eleni Giannoulatou, Helen Gogas, Christos Papadimitriou, Ioannis Tikas, Jianhua Zhang, Kyriaki Papadopoulou, Flora Zagouri, Christos Christodoulou, Angelos Koutras, Thomas Makatsoris, Sofia Chrisafi, Helena Linardou, Ioannis Varthalitis, George Papatsibas, Evangelia Razis, Pavlos Papakostas, Epaminontas Samantas, Gerasimos Aravantinos, Dimitrios Bafaloukos, Paris Kosmidis, Anna Koumarianou, Amanda Psyrri, Georgios Pentheroudakis, Dimitrios Pectasides, Andrew Futreal, George Fountzilas, Apostolia M Tsimberidou

Affiliations

  1. The University of Texas MD Anderson Cancer Center, Department of Investigational Cancer Therapeutics, Houston, TX, USA.
  2. Current address: Hellenic Cooperative Oncology Group, Athens, Greece.
  3. Department of Pathology, Aristotle University of Thessaloniki, School of Health Sciences, Faculty of Medicine, Thessaloniki, Greece.
  4. Laboratory of Molecular Oncology, Hellenic Foundation for Cancer Research/Aristotle University of Thessaloniki, Thessaloniki, Greece.
  5. Section of Biostatistics, Hellenic Cooperative Oncology Group, Data Office, Athens, Greece.
  6. Victor Chang Cardiac Research Institute, Darlinghurst, NSW, Australia.
  7. The University of New South Wales, Kensington, NSW, Australia.
  8. First Department of Medicine, Laiko General Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.
  9. Oncology Unit, Aretaieion Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.
  10. Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  11. Department of Clinical Therapeutics, Alexandra Hospital, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.
  12. Second Department of Medical Oncology, Metropolitan Hospital, Piraeus, Greece.
  13. Division of Oncology, Department of Medicine, University Hospital, University of Patras Medical School, Patras, Greece.
  14. Oncology Unit, Metropolitan Hospital, Piraeus, Greece.
  15. First Department of Medical Oncology, Henry Dunant Hospital, Athens, Greece.
  16. Oncology Department, University General Hospital of Larissa, Larissa, Greece.
  17. Third Department of Medical Oncology, Hygeia Hospital, Athens, Greece.
  18. Oncology Unit, Hippokration Hospital, Athens, Greece.
  19. Third Department of Medical Oncology, Agii Anargiri Cancer Hospital, Athens, Greece.
  20. Second Department of Medical Oncology, Agii Anargiri Cancer Hospital, Athens, Greece.
  21. First Department of Medical Oncology, Metropolitan Hospital, Piraeus, Greece.
  22. Second Department of Medical Oncology, Hygeia Hospital, Athens, Greece.
  23. Fourth Department of Internal Medicine, Attikon University Hospital, Athens, Greece.
  24. Section of Medical Oncology, Department of Internal Medicine, Attikon University Hospital, Faculty of Medicine, National and Kapodistrian University of Athens School of Medicine, Athens, Greece.
  25. Department of Medical Oncology, Medical School, University of Ioannina, Ioannina, Greece.
  26. Society for Study of Clonal Heterogeneity of Neoplasia (EMEKEN), Ioannina, Greece.
  27. Oncology Section, Second Department of Internal Medicine, Hippokration Hospital, Athens, Greece.
  28. The University of Texas MD Anderson Cancer Center, Department of Genomic Medicine, Houston, TX, USA.
  29. Aristotle University of Thessaloniki, Thessaloniki, Greece.

PMID: 32002119 PMCID: PMC6967777 DOI: 10.18632/oncotarget.27338

[No abstract available.]

Copyright: Fountzilas et al.

Keywords: actionable gene; next-generation sequencing; pathogenic mutation; precision oncology; prognosis

Conflict of interest statement

CONFLICTS OF INTEREST Fountzilas E: Travel: Merck, K.A.M. oncology/hematology, stock: Deciphera, Kotoula V: No conflict of interest (5/2019), Koliou GA: No conflict of interest (5/2019), Giannoulatou

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