Display options
Share it on

J Arrhythm. 2020 Jan 08;36(1):84-92. doi: 10.1002/joa3.12291. eCollection 2020 Feb.

Effectiveness of catheter ablation of atrial fibrillation according to heart failure etiology.

Journal of arrhythmia

Eric Black-Maier, Benjamin A Steinberg, Kevin M Trulock, Frances Wang, Yuliya Lokhnygina, Wanda O'Neal, Sana Al-Khatib, Brett D Atwater, James P Daubert, Camille Frazier-Mills, Donald D Hegland, Kevin P Jackson, Larry R Jackson, Jason I Koontz, Robert K Lewis, Albert Y Sun, Kevin L Thomas, Tristram D Bahnson, Jonathan P Piccini

Affiliations

  1. Cardiac Electrophysiology Section Duke Center for Atrial Fibrillation Duke University Medical Center Durham NC USA.
  2. Department of Biostatistics Duke University Durham NC USA.
  3. Electrophysiology Section University of Utah Salt Lake City UT USA.

PMID: 32071625 PMCID: PMC7011840 DOI: 10.1002/joa3.12291

Abstract

BACKGROUND: Catheter ablation is an important rhythm control therapy in patients with atrial fibrillation (AF) with concomitant heart failure (HF). The objective of this study was to assess the comparative efficacy of AF ablation patients with ischemic vs nonischemic heart failure.

METHODS: We conducted a retrospective, observational cohort study of patients with HF who underwent AF ablation. Outcomes were compared based on HF etiology and included in-hospital events, symptoms (Mayo AF Symptom Inventory [MAFSI]), and functional status (New York Heart Association class) and freedom from atrial arrhythmias at 12 months.

RESULTS: Among 242 patients (n = 70 [29%] ischemic, n = 172 [71%] nonischemic), patients with nonischemic cardiomyopathy were younger (mean age 64 ± 11.5 vs 69 ± 9.1,

CONCLUSIONS: Catheter ablation in patients with AF and concomitant heart failure leads to significant improvements in functional and symptom status without significant differences between patients with ischemic vs nonischemic HF etiology.

© 2020 The Authors. Journal of Arrhythmia published by John Wiley & Sons Australia, Ltd on behalf of the Japanese Heart Rhythm Society.

Keywords: atrial fibrillation; cardiomyopathy; catheter ablation; heart failure; outcomes

Conflict of interest statement

E. Black‐Maier: None. BA Steinberg: Fellowship Support; Medtronic, Inc, St. Jude Medical, Biotronik, Boston Scientific Corp. Fellowship Support; Biosense Webster, Inc.; Boston Scientific Corp., Jansse

References

  1. Heart Rhythm. 2011 Mar;8(3):377-82 - PubMed
  2. Heart. 2011 May;97(9):740-7 - PubMed
  3. Circ Arrhythm Electrophysiol. 2009 Aug;2(4):349-61 - PubMed
  4. Circulation. 1998 Sep 8;98(10):946-52 - PubMed
  5. J Am Coll Cardiol. 2014 Jan 28;63(3):251-8 - PubMed
  6. J Am Coll Cardiol. 2000 Oct;36(4):1303-9 - PubMed
  7. J Cardiovasc Electrophysiol. 2016 Mar;27(3):281-9 - PubMed
  8. J Card Fail. 2011 Nov;17(11):964-70 - PubMed
  9. N Engl J Med. 2008 Oct 23;359(17):1778-85 - PubMed
  10. N Engl J Med. 2002 Dec 5;347(23):1825-33 - PubMed
  11. Circulation. 2019 Jul 9;140(2):e125-e151 - PubMed
  12. Ann Intern Med. 2009 Aug 4;151(3):191-202 - PubMed
  13. Circulation. 2014 Feb 18;129(7):728-36 - PubMed
  14. J Am Coll Cardiol. 2001 Feb;37(2):371-8 - PubMed
  15. Circ Arrhythm Electrophysiol. 2014 Feb;7(1):31-8 - PubMed
  16. J Am Coll Cardiol. 2004 Mar 17;43(6):1004-9 - PubMed
  17. Heart. 2015 Jun;101(11):894-9 - PubMed
  18. Heart Rhythm. 2007 Jun;4(6):816-61 - PubMed
  19. Europace. 2014 Sep;16(9):1284-90 - PubMed
  20. N Engl J Med. 2012 Oct 25;367(17):1587-95 - PubMed
  21. BMC Cardiovasc Disord. 2019 Jan 15;19(1):18 - PubMed
  22. J Am Coll Cardiol. 2017 Oct 17;70(16):1949-1961 - PubMed
  23. J Clin Sleep Med. 2009 Jun 15;5(3):263-76 - PubMed
  24. Circulation. 2014 Feb 25;129(8):837-47 - PubMed
  25. N Engl J Med. 2008 Jun 19;358(25):2667-77 - PubMed
  26. JAMA. 2014 Feb 5;311(5):498-506 - PubMed
  27. J Am Coll Cardiol. 2013 May 7;61(18):1894-903 - PubMed
  28. Heart. 2016 Oct 1;102(19):1533-43 - PubMed
  29. Am J Cardiol. 2009 Dec 1;104(11):1534-9 - PubMed
  30. J Am Coll Cardiol. 2010 May 25;55(21):2308-16 - PubMed
  31. Circulation. 2016 Apr 26;133(17):1637-44 - PubMed
  32. N Engl J Med. 2018 Feb 01;378(5):417-427 - PubMed
  33. JAMA. 2019 Apr 2;321(13):1261-1274 - PubMed
  34. Heart Rhythm. 2016 Feb;13(2):383-90 - PubMed

Publication Types