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Germs. 2019 Dec 02;9(4):198-210. doi: 10.18683/germs.2019.1178. eCollection 2019 Dec.

Consensus statement on the assessment of comorbidities in people living with HIV in Romania.

Germs

Anca Streinu-Cercel, Oana Săndulescu, Cătălina Poiană, Maria Dorobanţu, Gabriel Mircescu, Voichiţa Elena Lăzureanu, Irina-Magdalena Dumitru, Odette Chirilă, Adrian Streinu-Cercel,

Affiliations

  1. MD, PhD, Associate Professor, Department of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Bal?", 1 Dr. Calistrat Grozovici Street, Bucharest 021105, Romania.
  2. MD, PhD, Professor, Department of Endocrinology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute of Endocrinology "C. I. Parhon", 34-38 Aviatorilor Boulevard, Bucharest 011863, Romania.
  3. MD, PhD, Professor, Department of Cardiology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Clinical Emergency Hospital Floreasca, 8 Floreasca Road, Bucharest 014461, Romania.
  4. MD, PhD, Professor, Department of Nephrology, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Clinical Nephrology Hospital "Carol Davila", 4 Grivi?ei Road, Bucharest 010731, Romania.
  5. MD, PhD, Associate Professor, Dr. Victor Babe? University of Medicine and Pharmacy, Timi?oara, "Victor Babe?" Clinical Hospital of Infectious Diseases and Pneumology, 2 Eftimie Murgu Plaza, Timi?oara, Romania.
  6. MD, PhD, Associate Professor, Clinical Hospital of Infectious Diseases Constan?a; Department of Infectious Diseases, Faculty of Medicine, Ovidius University of Constan?a, 124 Mamaia Boulevard, Constan?a, Romania.
  7. Principal Clinical Psychologist, National Institute for Infectious Diseases "Prof. Dr. Matei Bal?", 1 Dr. Calistrat Grozovici Street, Bucharest 021105, Romania.
  8. MD, PhD, Professor, Department of Infectious Diseases I, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, National Institute for Infectious Diseases "Prof. Dr. Matei Bal?", 1 Dr. Calistrat Grozovici Street, Bucharest 021105, Romania.

PMID: 32042727 PMCID: PMC6942655 DOI: 10.18683/germs.2019.1178

Abstract

INTRODUCTION: The life expectancy of HIV-infected patients has been increased by highly effective therapies. People living with HIV (PLWH) in Romania are exposed to age-related comorbidities occurring earlier than in uninfected individuals. Multidisciplinary care is required to maintain the general health and quality of life in these patients. Currently, the communication among different specialties needs to be enhanced and formalized.

METHODS: A panel consisting of 8 Romanian experts in infectious diseases, cardio-metabolic, bone, and kidney diseases and psychology met in May 2019 in Bucharest Romania to discuss the need to evaluate and monitor the most prevalent comorbidities in PLWH. The meeting resulted in practical guidance on the management of several non-infectious associated diseases. The algorithms were endorsed by the Society for Infectious Diseases and HIV/AIDS, Romania.

RESULTS: The consensus statement offers practical guidance on how to assess and monitor associated diseases in adult PLWH. The recommendations are grouped for each cluster of comorbidities and are based on international guidelines and clinical experience, including landmarks for referral of PLWH to cardiology, endocrinology, nephrology specialist or clinical psychologist for additional investigations and adequate treatment. Specific indications for diagnosis or treatment were beyond the scope of this consensus.

CONCLUSIONS: Screening for associated diseases and adequate management are required to maintain the overall health status of PLWH. When implemented in clinical practice, the recommended algorithms should be used in addition to diagnosis and treatment guidelines and protocols. The infectious diseases specialist plays a key role in coordinating the overall treatment strategy and working within the multidisciplinary team.

GERMS.

Keywords: HIV; PLWH; comorbidities; consensus statement; monitoring

Conflict of interest statement

Conflicts of interest: AnSC reports being sub-investigator in clinical trials by Merck and Gilead, principal investigator in an investigator sponsored research study funded by a Gilead grant, speaker

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