Front Psychiatry. 2020 Feb 18;10:933. doi: 10.3389/fpsyt.2019.00933. eCollection 2019.
Psychological and Psychosocial Interventions for PTSD, Depression and Anxiety Among Children and Adolescents in Low- and Middle-Income Countries: A Meta-Analysis.
Frontiers in psychiatry
Jana R Uppendahl, Cansu Alozkan-Sever, Pim Cuijpers, Ralph de Vries, Marit Sijbrandij
Affiliations
Affiliations
- Department of Clinical, Neuro and Developmental Psychology, World Health Organization Collaborating Center for Research and Dissemination of Psychological Interventions, Amsterdam Public Health Research Institute, Vrije Universiteit, Amsterdam, Netherlands.
- Medical Library, Vrije Universiteit, Amsterdam, Netherlands.
PMID: 32132936
PMCID: PMC7040217 DOI: 10.3389/fpsyt.2019.00933
Abstract
BACKGROUND: In low- and middle-income countries, rates of common mental health disorders are found to be very high among children and adolescents while individuals, particularly in these countries, face barriers to mental health care. In the recent years, randomized controlled trials (RCTs) have been conducted that implemented and tested different psychological and psychosocial treatment approaches to treat common mental disorders. This review aims to analyze psychological interventions among children and adolescents in low- and middle-income countries.
METHODS: RCTs carried out in low- and middle-income countries on psychological and psychosocial interventions for children and adolescents with symptoms of trauma- and stressor related disorders, depression or anxiety were identified in bibliographic databases. Databases were systematically searched until December 14, 2018. Effect sizes indicating differences between treatment and control groups at post-test were computed using a random-effects model. Outcomes were symptoms of depression, anxiety and posttraumatic stress disorder (PTSD).
RESULTS: Thirteen studies with a total of 2,626 participants aged between 5 and 18 years were included. Treatments varied between studies and number of treatment sessions ranged from 1 to 16. The pooled effect size, combining outcomes of depression, anxiety and PTSD of psychological or psychosocial intervention versus care-as-usual or a control conditions yielded a medium effect (
CONCLUSION: High quality RCTs investigating the effect of psychological and psychosocial interventions on PTSD, depression and anxiety among children and adolescents in low- and middle-income countries are scarce. Results of the available studies may suggest that psychological and psychosocial interventions might be more effective in reducing symptoms of anxiety, depression and PTSD compared to control conditions. Due to very high heterogeneity, this evidence must be considered with caution.
Copyright © 2020 Uppendahl, Alozkan-Sever, Cuijpers, de Vries and Sijbrandij.
Keywords: adolescents; anxiety; children; depression; low- and middle- income countries; meta-analysis; posttraumatic stress disorder; psychological therapy
References
- Eur J Psychotraumatol. 2019 Mar 25;10(1):1550344 - PubMed
- PLoS Med. 2009 Jul 21;6(7):e1000097 - PubMed
- Annu Rev Clin Psychol. 2017 May 8;13:149-181 - PubMed
- Lancet. 2016 Jun 11;387(10036):2383-401 - PubMed
- BMC Med. 2014 Apr 01;12:56 - PubMed
- Asian J Psychiatr. 2016 Oct;23:99-107 - PubMed
- Lancet. 2007 Sep 15;370(9591):991-1005 - PubMed
- BMJ. 2010 Mar 23;340:c869 - PubMed
- Psychother Psychosom. 2009;78(5):275-84 - PubMed
- Am J Clin Hypn. 2009 Jul;52(1):23-34 - PubMed
- J Am Acad Child Adolesc Psychiatry. 2012 Dec;51(12):1261-72 - PubMed
- J Clin Psychol. 2016 Mar;72(3):226-48 - PubMed
- Acta Psychiatr Scand. 2014 Sep;130(3):181-92 - PubMed
- Eur Child Adolesc Psychiatry. 2005 Aug;14(5):262-9 - PubMed
- J Child Psychol Psychiatry. 2010 Jul;51(7):818-26 - PubMed
- JAMA. 2004 Jun 2;291(21):2581-90 - PubMed
- Trials. 2019 Sep 2;20(1):545 - PubMed
- Biometrics. 2000 Jun;56(2):455-63 - PubMed
- J Clin Psychiatry. 2008 Sep;69(9):1469-76 - PubMed
- Eur J Psychotraumatol. 2017 Nov 07;8(sup2):1388102 - PubMed
- JAMA Pediatr. 2015 Aug;169(8):761-9 - PubMed
- Curr Psychiatry Rep. 2016 Jan;18(1):9 - PubMed
- World Psychiatry. 2016 Oct;15(3):245-258 - PubMed
- Lancet Psychiatry. 2018 Mar;5(3):237-286 - PubMed
- PLoS Med. 2018 Mar 9;15(3):e1002524 - PubMed
- JMIR Ment Health. 2016 Sep 26;3(3):e44 - PubMed
- Lancet Glob Health. 2018 Apr;6(4):e390-e400 - PubMed
- Depress Anxiety. 2016 May;33(5):400-14 - PubMed
- World Psychiatry. 2012 Jun;11(2):114-22 - PubMed
- Soc Psychiatry Psychiatr Epidemiol. 2013 Apr;48(4):595-611 - PubMed
- Cochrane Database Syst Rev. 2018 Jul 05;7:CD011849 - PubMed
- J Am Acad Child Adolesc Psychiatry. 2012 Dec;51(12):1236-7 - PubMed
- Br J Psychiatry. 2017 Apr;210(4):247-254 - PubMed
- J Child Psychol Psychiatry. 2014 Apr;55(4):313-27 - PubMed
- JAMA. 2008 Aug 13;300(6):655-62 - PubMed
- Cochrane Database Syst Rev. 2012 Dec 12;12:CD006726 - PubMed
- J Trauma Stress. 2010 Aug;23(4):437-45 - PubMed
- JAMA. 2007 Aug 1;298(5):519-27 - PubMed
- BMJ. 2007 Nov 3;335(7626):914-6 - PubMed
- Asian J Psychiatr. 2018 Dec;38:78-91 - PubMed
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