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Cell Host Microbe. 2020 Feb 12;27(2):169-172. doi: 10.1016/j.chom.2020.01.022.

Therapeutics Targeting the Gut Microbiome: Rigorous Pipelines for Drug Development.

Cell host & microbe

Kate A Markey, Marcel R M van den Brink, Jonathan U Peled

Affiliations

  1. Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA. Electronic address: [email protected].
  2. Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA; Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  3. Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Medical College, New York, NY, USA.

PMID: 32053786 DOI: 10.1016/j.chom.2020.01.022

Abstract

Restoration of the gut microbiome is a promising preventive and therapeutic strategy in a number of clinical scenarios. We discuss here the scientific and clinical challenges of engineering and implementing these strategies.

Copyright © 2020. Published by Elsevier Inc.

Conflict of interest statement

Declaration of Interests M.R.M.v.d.B. has received research support from Seres Therapeutics; has consulted, received honorarium from, or participated in advisory boards for Seres Therapeutics, Flagshi

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