Niger J Surg. 2020 Jan-Jun;26(1):66-71. doi: 10.4103/njs.NJS_9_19. Epub 2020 Feb 10.
Factors Determining Diabetic Remission after Sleeve Gastrectomy: A Prospective Study.
Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society
Rohit Jindal, Mayank Gupta, Ashish Ahuja, Prabhdeep Singh Nain, Pranjl Sharma, Aayushi Aggarwal
Affiliations
Affiliations
- Department of General Surgery, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
- Department of Community Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
PMID: 32165840
PMCID: PMC7041342 DOI: 10.4103/njs.NJS_9_19
Abstract
BACKGROUND: An exponential rise in the prevalence of obesity and the associated type 2 diabetes mellitus (T2DM) has led to an explosion in the field of bariatric surgery worldwide. It has been proposed that laparoscopic sleeve gastrectomy (LSG) not only results in excess weight loss (EWL) but also leads to excellent glycemic control.
AIMS: However, not every patient benefits from the bariatric surgery. Furthermore, bariatric surgery is currently indicated based on body mass index (BMI), but BMI solely does not predict diabetes remission after the surgery. We aimed to study the outcome of LSG on the diabetic status and the factors predicting the disease remission.
SUBJECTS AND METHODS: This prospective study was conducted on 104 obese patients having T2DM who underwent LSG. Following surgery, the clinical outcome on weight loss, BMI, and glycemic control was studied for 6 months. Various positive and negative predictors of diabetic remission after the surgery were also determined. Student's
RESULTS: LSG resulted in significant weight loss (
CONCLUSION: LSG is a successful treatment option for T2DM and is more beneficial if offered, not as a last option, but to younger, obese patients with mild disease severity and shorter disease duration after the failure of medical treatment.
Copyright: © 2020 Nigerian Journal of Surgery.
Keywords: Bariatric surgery; diabetes remission; laparoscopic sleeve gastrectomy; predictor; type 2 diabetes mellitus
Conflict of interest statement
There are no conflicts of interest.
References
- Obes Surg. 2005 May;15(5):612-7 - PubMed
- Asian J Surg. 2012 Apr;35(2):67-73 - PubMed
- Diabetes Care. 2008 Feb;31 Suppl 2:S290-6 - PubMed
- J Gastrointest Surg. 2008 May;12(5):945-52 - PubMed
- Am Fam Physician. 1991 Jul;44(1):305-6 - PubMed
- Obes Surg. 2011 Aug;21(8):1168-71 - PubMed
- Nutr Clin Pract. 2007 Feb;22(1):22-8 - PubMed
- Ann Surg. 2003 Oct;238(4):467-84; discussion 84-5 - PubMed
- Surg Obes Relat Dis. 2013 May-Jun;9(3):379-84 - PubMed
- Diabetes Care. 2002 Feb;25(2):358-63 - PubMed
- Obes Surg. 2013 Jun;23(6):770-5 - PubMed
- Surg Obes Relat Dis. 2010 Mar 4;6(2):142-5 - PubMed
- Surg Obes Relat Dis. 2011 Nov-Dec;7(6):691-6 - PubMed
- Surg Endosc. 2010 Oct;24(10):2513-7 - PubMed
- Obes Surg. 2012 Jun;22(6):866-71 - PubMed
- Surg Obes Relat Dis. 2009 Jul-Aug;5(4):429-34 - PubMed
- Lancet. 2015 Sep 5;386(9997):964-73 - PubMed
- Diabetes Care. 2013 Jan;36(1):20-6 - PubMed
- Ann Surg. 2010 Jun;251(6):1049-55 - PubMed
- Obes Surg. 2012 Oct;22(10):1521-6 - PubMed
- Diabetes Care. 2003 Jan;26 Suppl 1:S5-20 - PubMed
- Surg Endosc. 2010 May;24(5):1005-10 - PubMed
- Curr Diab Rep. 2014;14(5):481 - PubMed
- Am J Med. 2009 Mar;122(3):248-256.e5 - PubMed
- Obes Facts. 2013;6(2):176-84 - PubMed
- J Assoc Physicians India. 2009 Feb;57:163-70 - PubMed
- Diabetes Metab Syndr Obes. 2015 Jun 08;8:255-62 - PubMed
- Obes Surg. 2010 Sep;20(9):1245-50 - PubMed
Publication Types