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Choi YY. Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea. J Korean Assoc Oral Maxillofac Surg. 2020;46(1):49-57doi: 10.5125/jkaoms.2020.46.1.49.
Choi, Y. Y. (2020). Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea. Journal of the Korean Association of Oral and Maxillofacial Surgeons, 46(1), 49-57. https://doi.org/10.5125/jkaoms.2020.46.1.49
Choi, Yoon-Young. "Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea." Journal of the Korean Association of Oral and Maxillofacial Surgeons vol. 46,1 (2020): 49-57. doi: https://doi.org/10.5125/jkaoms.2020.46.1.49
Choi YY. Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea. J Korean Assoc Oral Maxillofac Surg. 2020 Feb;46(1):49-57. doi: 10.5125/jkaoms.2020.46.1.49. Epub 2020 Feb 26. PMID: 32158681; PMCID: PMC7049760.
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J Korean Assoc Oral Maxillofac Surg. 2020 Feb;46(1):49-57. doi: 10.5125/jkaoms.2020.46.1.49. Epub 2020 Feb 26.

Prescription of antibiotics after tooth extraction in adults: a nationwide study in Korea.

Journal of the Korean Association of Oral and Maxillofacial Surgeons

Yoon-Young Choi

Affiliations

  1. Graduate School of Clinical Dentistry, Korea University, Seoul, Korea.
  2. Private Practice, Anyang, Korea.

PMID: 32158681 PMCID: PMC7049760 DOI: 10.5125/jkaoms.2020.46.1.49

Abstract

OBJECTIVES: This study aimed to understand the nationwide patterns of antibiotic prescription after tooth extraction in adult patients.

MATERIALS AND METHODS: This study analyzed dental records from the National Health Insurance Service-National Sample Cohort (NHIS-NSC) database on 503,725 tooth extractions performed in adults (≥19 years) during 2011-2015. Patient sex, age, household income, systemic disease (diabetes mellitus and hypertension), type of dental institution, region of dental institution, year of prescription, and type of tooth extraction procedure were considered. The antibiotic prescription rate and broad-spectrum antibiotic prescription frequency were analyzed using chi-squared tests. Factors affecting the prescription of broad-spectrum antibiotics were evaluated using multivariate logistic regression analysis.

RESULTS: The rate of antibiotic prescription after tooth extraction was 81.85%. Penicillin was most commonly prescribed (45.25%), followed by penicillin with beta-lactamase inhibitors (18.76%), metronidazole (12.29%), and second- to fourth-generation cephalosporins (11.52%). The proportion of broad-spectrum antibiotics used among all prescribed antibiotics was 45.88%.

CONCLUSION: The findings of this study demonstrate that the rate of antibiotic prescription after tooth extraction is higher in Korea than in other countries. Furthermore, broad-spectrum antibiotics are used more frequently, which may indicate unnecessary drug prescription, an important contributor to antibiotic resistance.

Copyright © 2020 The Korean Association of Oral and Maxillofacial Surgeons.

Keywords: Anti-bacterial agents; Antibiotics; Korea; Prescriptions; Tooth extraction

Conflict of interest statement

Conflict of Interest: No potential conflict of interest relevant to this article was reported.

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