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Tadic M, Cuspidi C, Plein S, et al. Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus. Heart Fail Rev. 2021;26(6):1383-1390doi: 10.1007/s10741-020-09943-x.
Tadic, M., Cuspidi, C., Plein, S., Milivojevic, I. G., Wang, D. W., Grassi, G., & Mancia, G. (2021). Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus. Heart failure reviews, 26(6), 1383-1390. https://doi.org/10.1007/s10741-020-09943-x
Tadic, Marijana, et al. "Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus." Heart failure reviews vol. 26,6 (2021): 1383-1390. doi: https://doi.org/10.1007/s10741-020-09943-x
Tadic M, Cuspidi C, Plein S, Milivojevic IG, Wang DW, Grassi G, Mancia G. Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus. Heart Fail Rev. 2021 Nov;26(6):1383-1390. doi: 10.1007/s10741-020-09943-x. PMID: 32170529.
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Heart Fail Rev. 2021 Nov;26(6):1383-1390. doi: 10.1007/s10741-020-09943-x.

Comprehensive assessment of hypertensive heart disease: cardiac magnetic resonance in focus.

Heart failure reviews

Marijana Tadic, Cesare Cuspidi, Sven Plein, Isidora Grozdic Milivojevic, Dao Wen Wang, Guido Grassi, Giuseppe Mancia

Affiliations

  1. Department of Cardiology, University Hospital "Dr. Dragisa Misovic - Dedinje", Heroja Milana Tepica 1, Belgrade, 11000, Serbia. [email protected].
  2. University of Milan-Bicocca, Milan, Italy.
  3. Istituto Auxologico Italiano, Clinical Research Unit, Viale della Resistenza 23, 20036, Meda, Italy.
  4. Department of Biomedical Imaging Science, Leeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
  5. Center for Nuclear Medicine Clinical Center of Serbia, Belgrade, Serbia.
  6. Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
  7. Department of Internal Medicine, Division of Cardiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
  8. Hubei Key Laboratory of Genetics and Molecular Mechanisms of Cardiologic Disorders, Wuhan, 430030, Hubei Province, China.
  9. Policlinico di Monza, Monza, Italy.

PMID: 32170529 DOI: 10.1007/s10741-020-09943-x

Abstract

Arterial hypertension represents the most frequent cardiovascular risk factor that is associated with cardiac remodeling. Hypertensive heart disease was defined by the presence of left ventricular hypertrophy (LVH) and diastolic dysfunction, and it has been diagnosed by echocardiography in everyday clinical practice. Interstitial myocardial fibrosis is the underlying cause of hypertension-induced cardiac remodeling, and it could not be visualized with different echocardiographic methods. Cardiac magnetic resonance (CMR) and its methods such as late gadolinium enhancement, and T1 mapping provides qualitative and quantitative assessment of interstitial myocardial fibrosis in hypertensive patients. Furthermore, CMR can provide differentiation of LVH between hypertensive patients and cardiomyopathies (hypertrophic or Fabry disease). Timely diagnosis of cardiac impairment and early treatment is essential because regression of LVH could be achieved with adequate treatment. Diffuse cardiac fibrosis in hypertensive patients might be an underlying mechanism that explains the increased cardiovascular morbidity and mortality in this population. Future longitudinal investigations are necessary to determine causal relationship between diffuse fibrosis and cardiovascular outcome in these patients. The aim of this review is to summarize the current knowledge regarding CMR techniques and their potential usage in patients with hypertensive heart disease.

© 2020. Springer Science+Business Media, LLC, part of Springer Nature.

Keywords: Cardiac magnetic resonance; Late gadolinium enhancement; Left ventricle; Strain; T1 mapping

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