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Dhaliwal R, Hans D, Hattersley G, et al. Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study. JBMR Plus. 2020;4(4):e10346doi: 10.1002/jbm4.10346.
Dhaliwal, R., Hans, D., Hattersley, G., Mitlak, B., Fitzpatrick, L. A., Wang, Y., Schwartz, A. V., Miller, P. D., & Josse, R. G. (2020). Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study. JBMR plus, 4(4), e10346. https://doi.org/10.1002/jbm4.10346
Dhaliwal, Ruban, et al. "Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study." JBMR plus vol. 4,4 (2020): e10346. doi: https://doi.org/10.1002/jbm4.10346
Dhaliwal R, Hans D, Hattersley G, Mitlak B, Fitzpatrick LA, Wang Y, Schwartz AV, Miller PD, Josse RG. Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study. JBMR Plus. 2020 Feb 27;4(4):e10346. doi: 10.1002/jbm4.10346. eCollection 2020 Apr. PMID: 32258965; PMCID: PMC7117849.
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JBMR Plus. 2020 Feb 27;4(4):e10346. doi: 10.1002/jbm4.10346. eCollection 2020 Apr.

Abaloparatide in Postmenopausal Women With Osteoporosis and Type 2 Diabetes: A Post Hoc Analysis of the ACTIVE Study.

JBMR plus

Ruban Dhaliwal, Didier Hans, Gary Hattersley, Bruce Mitlak, Lorraine A Fitzpatrick, Yamei Wang, Ann V Schwartz, Paul D Miller, Robert G Josse

Affiliations

  1. Metabolic Bone Disease Center State University of New York Upstate Medical University Syracuse NY USA.
  2. Center of Bone Disease, Bones & Joints Department Lausanne University Hospital Lausanne Switzerland.
  3. Clinical Development, Radius Health, Inc. Waltham MA USA.
  4. Biostatistics, Radius Health, Inc. Waltham MA USA.
  5. Department of Epidemiology and Biostatistics UCSF School of Medicine San Francisco CA USA.
  6. Research, Colorado Center for Bone Research Lakewood CO USA.
  7. Research, St. Michael's Hospital University of Toronto Toronto Canada.

PMID: 32258965 PMCID: PMC7117849 DOI: 10.1002/jbm4.10346

Abstract

Type 2 diabetes mellitus (T2DM) increases fracture risk despite normal or increased BMD. Abaloparatide reduces fracture risk in patients with postmenopausal osteoporosis (PMO); however, its efficacy in women with T2DM is unknown. This post hoc analysis evaluated the efficacy and safety of abaloparatide in patients with T2DM. The analysis included patients with T2DM from the

© 2020 The Authors. JBMR Plus published by Wiley Periodicals, Inc. on behalf of American Society for Bone and Mineral Research.

Keywords: ABALOPARATIDE; ANABOLICS; BONE MINERAL DENSITY; CLINICAL TRIALS; DXA; FRACTURE PREVENTION; OSTEOPOROSIS; TRABECULAR BONE SCORE; TYPE 2 DIABETES MELLITUS

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