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Case Rep Ophthalmol Med. 2020 Mar 13;2020:7049168. doi: 10.1155/2020/7049168. eCollection 2020.

Management of Acute Posterior Multifocal Placoid Pigment Epitheliopathy (APMPPE): Insights from Multimodal Imaging with OCTA.

Case reports in ophthalmological medicine

Mariana A Oliveira, Jorge Simão, Amélia Martins, Cláudia Farinha

Affiliations

  1. Department of Ophthalmology, Centro Hospitalar e Universitário de Coimbra (CHUC), Coimbra, Portugal.
  2. Coimbra Institute for Clinical and Biomedical Research, Faculty of Medicine, University of Coimbra (iCBR-FMUC), Coimbra, Portugal.
  3. Association for Innovation and Biomedical Research on Light and Imaging (AIBILI), Coimbra, Portugal.

PMID: 32231829 PMCID: PMC7094199 DOI: 10.1155/2020/7049168

Abstract

A 28-year-old man presented to the emergency room with blurred vision in the right eye for two days. He reported a preceding flu-like illness one week earlier. His best-corrected visual acuity (BCVA) was 20/40 in the right eye and 20/25 in the left eye. There was no anterior chamber inflammation or vitritis in either eye. He presented multiple yellowish-white placoid lesions in the posterior pole, some involving the foveal area, bilaterally. General examination and systemic investigation were unremarkable. Multimodal evaluation with fluorescein angiography, indocyanine green angiography, and spectral domain and optical coherence tomography angiography (OCTA) were consistent with the diagnosis of acute posterior multifocal placoid pigment epitheliopathy. Due to centromacular involvement with decreased BCVA, treatment with oral methylprednisolone was started after infectious causes were ruled out. After two weeks, the patient presented functional and anatomical improvement. OCTA showed partial reperfusion of the choriocapillaris in the affected areas, in both eyes.

Copyright © 2020 Mariana A. Oliveira et al.

Conflict of interest statement

The authors declare that there is no conflict of interests regarding the publication of this paper.

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