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Respirol Case Rep. 2020 Apr 07;8(4):e00555. doi: 10.1002/rcr2.555. eCollection 2020 May.

Relapse of cervical tuberculous lymphadenitis immediately after completion of effective anti-tuberculosis treatments.

Respirology case reports

Yuya Kimura, Masahiro Shimada, Masahiro Kawashima, Akira Yamane, Hideaki Nagai, Hirotoshi Matsui

Affiliations

  1. Center for Pulmonary Diseases National Hospital Organization Tokyo National Hospital Tokyo Japan.

PMID: 32269777 PMCID: PMC7136954 DOI: 10.1002/rcr2.555

Abstract

Most cases of lymph node enlargement after completing tuberculosis (TB) treatment are due to paradoxical reaction (PR), not relapse, and therefore, do not require re-treatment. We herein report a case of a 28-year-old man who had developed cervical TB lymphadenitis and exhibited re-enlargement of the same lymph nodes one month after completing effective TB chemotherapy, which was microbiologically proven as relapse. The patient noticed painful cervical lymphadenopathy one month after completion of chemotherapy for TB lymphadenitis. Combination chemotherapy with multiple anti-TB drugs was resumed with suspicion of relapse. But, with his symptoms having worsened, surgical excision was performed.

© 2020 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology.

Keywords: Cervical tuberculous lymphadenitis; paradoxical reaction; relapse; surgical excision

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