Display options
Cite
Piel FB, Fecht D, Hodgson S, et al. Small-area methods for investigation of environment and health. Int J Epidemiol. 2020;49(2):686-699doi: 10.1093/ije/dyaa006.
Piel, F. B., Fecht, D., Hodgson, S., Blangiardo, M., Toledano, M., Hansell, A. L., & Elliott, P. (2020). Small-area methods for investigation of environment and health. International journal of epidemiology, 49(2), 686-699. https://doi.org/10.1093/ije/dyaa006
Piel, Frédéric B, et al. "Small-area methods for investigation of environment and health." International journal of epidemiology vol. 49,2 (2020): 686-699. doi: https://doi.org/10.1093/ije/dyaa006
Piel FB, Fecht D, Hodgson S, Blangiardo M, Toledano M, Hansell AL, Elliott P. Small-area methods for investigation of environment and health. Int J Epidemiol. 2020 Apr 01;49(2):686-699. doi: 10.1093/ije/dyaa006. PMID: 32182344; PMCID: PMC7266556.
Copy Download .nbib Format: NLM
Share it on

Int J Epidemiol. 2020 Apr 01;49(2):686-699. doi: 10.1093/ije/dyaa006.

Small-area methods for investigation of environment and health.

International journal of epidemiology

Frédéric B Piel, Daniela Fecht, Susan Hodgson, Marta Blangiardo, M Toledano, A L Hansell, Paul Elliott

Affiliations

  1. UK Small Area Health Statistics Unit, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, UK.
  2. MRC-PHE Centre for Environment & Health, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, UK.
  3. National Institute for Health Research Health Protection Research Unit (NIHR HPRU) in Health Impact of Environmental Hazards, Imperial College London, UK.
  4. Centre for Environmental Health and Sustainability, Medical School, University of Leicester, Leicester, UK.

PMID: 32182344 PMCID: PMC7266556 DOI: 10.1093/ije/dyaa006

Abstract

Small-area studies offer a powerful epidemiological approach to study disease patterns at the population level and assess health risks posed by environmental pollutants. They involve a public health investigation on a geographical scale (e.g. neighbourhood) with overlay of health, environmental, demographic and potential confounder data. Recent methodological advances, including Bayesian approaches, combined with fast-growing computational capabilities, permit more informative analyses than previously possible, including the incorporation of data at different scales, from satellites to individual-level survey information. Better data availability has widened the scope and utility of small-area studies, but has also led to greater complexity, including choice of optimal study area size and extent, duration of study periods, range of covariates and confounders to be considered and dealing with uncertainty. The availability of data from large, well-phenotyped cohorts such as UK Biobank enables the use of mixed-level study designs and the triangulation of evidence on environmental risks from small-area and individual-level studies, therefore improving causal inference, including use of linked biomarker and -omics data. As a result, there are now improved opportunities to investigate the impacts of environmental risk factors on human health, particularly for the surveillance and prevention of non-communicable diseases.

© The Author(s) 2020. Published by Oxford University Press on behalf of the International Epidemiological Association.

References

  1. BMC Med Res Methodol. 2015 Apr 07;15:30 - PubMed
  2. J Epidemiol Community Health. 1995 Dec;49 Suppl 2:S30-3 - PubMed
  3. BMJ. 2010 Jun 22;340:c3077 - PubMed
  4. Occup Environ Med. 2007 Jun;64(6):380-8 - PubMed
  5. Epidemiology. 2016 Nov;27(6):810-8 - PubMed
  6. Thorax. 2007 Dec;62(12):1088-94 - PubMed
  7. J Public Health (Oxf). 2006 Mar;28(1):71-81 - PubMed
  8. Environ Health Perspect. 2009 Oct;117(10):1486-93 - PubMed
  9. Eur Respir J. 2017 Jan 11;49(1): - PubMed
  10. BMJ. 2013 Oct 08;347:f5432 - PubMed
  11. Arch Dis Child Fetal Neonatal Ed. 2016 Sep;101(5):F451-7 - PubMed
  12. Lancet. 2018 Jan 27;391(10118):339-349 - PubMed
  13. Biostatistics. 2012 Sep;13(4):695-710 - PubMed
  14. Environ Pollut. 2015 Mar;198:201-10 - PubMed
  15. Epidemiology. 2013 Mar;24(2):184-90 - PubMed
  16. Crit Rev Toxicol. 2014 May;44(5):450-66 - PubMed
  17. Biostatistics. 2019 Jan 1;20(1):1-16 - PubMed
  18. Toxicol Lett. 2004 Apr 1;149(1-3):235-42 - PubMed
  19. Stat Methods Med Res. 2016 Aug;25(4):1145-65 - PubMed
  20. Cancer Epidemiol Biomarkers Prev. 2016 Oct;25(10):1402-1410 - PubMed
  21. Int J Epidemiol. 2020 Apr 1;49(Supplement_1):i4-i14 - PubMed
  22. Environ Int. 2016 Mar;88:235-242 - PubMed
  23. Lancet. 1998 Aug 8;352(9126):423-7 - PubMed
  24. BMJ. 2005 Jan 1;330(7481):27 - PubMed
  25. J Public Health (Oxf). 2018 Jun 1;40(2):419-425 - PubMed
  26. Lancet Public Health. 2016 Dec 16;2(1):e15-e22 - PubMed
  27. J Expo Sci Environ Epidemiol. 2017 Nov;27(6):575-581 - PubMed
  28. Int J Epidemiol. 2020 Apr 1;49(Supplement_1):i57-i66 - PubMed
  29. Biostatistics. 2018 Sep 25;: - PubMed
  30. Environ Int. 2019 Jan;122:151-158 - PubMed
  31. Appl Geogr. 2014 Jan;46:147-157 - PubMed
  32. Environ Res. 2014 Oct;134:280-5 - PubMed
  33. BMJ. 2001 Aug 18;323(7309):363-8 - PubMed
  34. Environ Geochem Health. 2015 Aug;37(4):631-49 - PubMed
  35. Environ Health Perspect. 2015 Jul;123(7):697-704 - PubMed
  36. Eur Heart J. 2015 Oct 14;36(39):2653-61 - PubMed
  37. Thorax. 2016 Apr;71(4):330-8 - PubMed
  38. Int J Epidemiol. 2020 Apr 1;49(Supplement_1):i49-i56 - PubMed
  39. Occup Environ Med. 2007 Sep;64(9):633-8 - PubMed
  40. Community Med. 1981 May;3(2):131-9 - PubMed
  41. Lancet. 2018 Feb 10;391(10120):581-630 - PubMed
  42. J Public Health Med. 1999 Sep;21(3):289-98 - PubMed
  43. World Health Stat Q. 1995;48(2):85-94 - PubMed
  44. Int J Epidemiol. 2001 Oct;30(5):1100-8 - PubMed
  45. BMJ. 2017 Dec 5;359:j5299 - PubMed
  46. Spat Spatiotemporal Epidemiol. 2019 Nov;31:100301 - PubMed
  47. Tob Control. 2003 Mar;12(1):79-85 - PubMed
  48. Int J Epidemiol. 2020 Apr 1;49(Supplement_1):i26-i37 - PubMed
  49. Environ Sci Technol. 2017 Jun 20;51(12):6634-6647 - PubMed
  50. Environ Pollut. 2016 Jan;208(Pt A):48-57 - PubMed
  51. Sci Total Environ. 2012 Jan 1;414:6-21 - PubMed
  52. Malays J Med Sci. 2000 Jan;7(1):10-5 - PubMed
  53. Annu Rev Stat Appl. 2017 Mar;4:245-266 - PubMed
  54. Environ Int. 2014 Aug;69:120-32 - PubMed
  55. Environ Pollut. 2016 Jan;208(Pt A):25-32 - PubMed
  56. J Occup Med. 1974 Mar;16(3):150-1 - PubMed
  57. Environ Health Perspect. 2004 Jun;112(9):998-1006 - PubMed
  58. J Epidemiol Community Health. 2000 Jan;54(1):75-6 - PubMed
  59. Int J Equity Health. 2013 Aug 20;12:66 - PubMed
  60. Caspian J Intern Med. 2011 Fall;2(4):289-98 - PubMed
  61. Biostatistics. 2009 Apr;10(2):335-51 - PubMed
  62. Lancet. 1992 May 23;339(8804):1268-78 - PubMed
  63. PLoS Med. 2015 Mar 31;12(3):e1001779 - PubMed
  64. Annu Rev Public Health. 2000;21:171-92 - PubMed
  65. Noise Health. 2017 Nov-Dec;19(91):245-253 - PubMed
  66. PLoS One. 2010 May 20;5(5):e10746 - PubMed
  67. J Epidemiol Community Health. 1995 Dec;49 Suppl 2:S72-7 - PubMed
  68. Health Policy. 2012 Apr;105(1):10-6 - PubMed
  69. Int J Health Geogr. 2016 Apr 21;15:14 - PubMed
  70. Environ Health Perspect. 2008 Aug;116(8):1098-104 - PubMed
  71. Soc Sci Med. 2008 Nov;67(10):1612-29 - PubMed
  72. J Public Health (Oxf). 2018 Dec 1;40(4):e594-e600 - PubMed
  73. Environ Sci Technol. 2017 Jul 5;51(13):7511-7519 - PubMed
  74. Radiat Res. 2018 Jan;189(1):5-18 - PubMed
  75. BMJ. 2015 May 22;350:h2757 - PubMed

MeSH terms

Publication Types

Grant support