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Mol Biol. 2010;44(6):875-882. doi: 10.1134/S002689331006004X. Epub 2010 Dec 04.

Polymorphism of 2'-5'-oligoadenylate synthetase (.

Molecular biology

A V Barkhash, V N Babenko, V F Kobzev, A G Romaschenko, M I Voevoda

Affiliations

  1. 1Institute of Cytology and Genetics, Russian Academy of Sciences, Siberian Branch, Novosibirsk, 630090 Russia.
  2. 2Institute of Internal Medicine, Russian Academy of Medical Sciences, Siberian Branch, Novosibirsk, 630089 Russia.

PMID: 32214471 PMCID: PMC7088653 DOI: 10.1134/S002689331006004X

Abstract

2'-5'-oligoadenylate synthetases are a family of interferon-induced enzymes playing an important role in antiviral defense in mammals. In the human genome, three genes encoding functional synthetases (

© Pleiades Publishing, Ltd. 2010.

Keywords: 2′-5′-oligoadenylate synthetase genes; haplotypes; human populations of North Eurasia; linkage disequilibrium; predisposition to severe forms of tick-borne encephalitis; single nucleotide polymorphism (SNP)

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