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De Vitis R, Passiatore M, Perna A, et al. Seven-year clinical outcomes after collagenase injection in patients with Dupuytren's disease: A prospective study. J Orthop. 2020;21:218-222doi: 10.1016/j.jor.2020.03.028.
De Vitis, R., Passiatore, M., Perna, A., Careri, S., Cilli, V., & Taccardo, G. (2020). Seven-year clinical outcomes after collagenase injection in patients with Dupuytren's disease: A prospective study. Journal of orthopaedics, 21218-222. https://doi.org/10.1016/j.jor.2020.03.028
De Vitis, Rocco, et al. "Seven-year clinical outcomes after collagenase injection in patients with Dupuytren's disease: A prospective study." Journal of orthopaedics vol. 21 (2020): 218-222. doi: https://doi.org/10.1016/j.jor.2020.03.028
De Vitis R, Passiatore M, Perna A, Careri S, Cilli V, Taccardo G. Seven-year clinical outcomes after collagenase injection in patients with Dupuytren's disease: A prospective study. J Orthop. 2020 Mar 29;21:218-222. doi: 10.1016/j.jor.2020.03.028. eCollection 2020. PMID: 32273660; PMCID: PMC7132050.
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J Orthop. 2020 Mar 29;21:218-222. doi: 10.1016/j.jor.2020.03.028. eCollection 2020.

Seven-year clinical outcomes after collagenase injection in patients with Dupuytren's disease: A prospective study.

Journal of orthopaedics

Rocco De Vitis, Marco Passiatore, Andrea Perna, Silvia Careri, Vitale Cilli, Giuseppe Taccardo

Affiliations

  1. Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
  2. Università Cattolica del Sacro Cuore, Roma, Italy.
  3. Ospedale Pediatrico Bambino Gesù, Roma, Italy.
  4. Chirurgie de la main, CHIREC site Delta, Bruxelles, Italy.

PMID: 32273660 PMCID: PMC7132050 DOI: 10.1016/j.jor.2020.03.028

Abstract

INTRODUCTION: This investigation is a prospective cohort study examining the use of

METHODS: Forty-five monodigital DD patients were injected with CCH on a single joint. Assessment included measurement of residual passive extension deficit (PED), function (using QuickDASH) and patient satisfaction.

RESULTS: 86.7% of PIPJ and 65.6% of MPJ had a worsening of PED. Nevertheless, thirty-nine patients (86.7%) concluded their treatment with only one injection, without any further treatment.

CONCLUSION: CCH provides a long-term effective solution. Recurrence occurs, especially in PIPJ, with acceptable rates.

© 2020 Professor P K Surendran Memorial Education Foundation. Published by Elsevier B.V. All rights reserved.

Keywords: Collagenase injection; Dupuytren; Hand function; Recurrence rate; Seven years

Conflict of interest statement

The authors report no conflicts of interest.

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