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Nallanchakrava S, Mallela MK, Jeenepalli VSK, et al. A rare case report of neurofibromatosis type 1 in a 12-year-old child: A 15-month follow-up. J Oral Maxillofac Pathol. 2020;24:S106-S109doi: 10.4103/jomfp.JOMFP_35_20.
Nallanchakrava, S., Mallela, M. K., Jeenepalli, V. S. K., & Niharika, H. M. (2020). A rare case report of neurofibromatosis type 1 in a 12-year-old child: A 15-month follow-up. Journal of oral and maxillofacial pathology : JOMFP, 24S106-S109. https://doi.org/10.4103/jomfp.JOMFP_35_20
Nallanchakrava, Srinivas, et al. "A rare case report of neurofibromatosis type 1 in a 12-year-old child: A 15-month follow-up." Journal of oral and maxillofacial pathology : JOMFP vol. 24 (2020): S106-S109. doi: https://doi.org/10.4103/jomfp.JOMFP_35_20
Nallanchakrava S, Mallela MK, Jeenepalli VSK, Niharika HM. A rare case report of neurofibromatosis type 1 in a 12-year-old child: A 15-month follow-up. J Oral Maxillofac Pathol. 2020 Feb;24:S106-S109. doi: 10.4103/jomfp.JOMFP_35_20. Epub 2020 Feb 28. PMID: 32189916; PMCID: PMC7069136.
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J Oral Maxillofac Pathol. 2020 Feb;24:S106-S109. doi: 10.4103/jomfp.JOMFP_35_20. Epub 2020 Feb 28.

A rare case report of neurofibromatosis type 1 in a 12-year-old child: A 15-month follow-up.

Journal of oral and maxillofacial pathology : JOMFP

Srinivas Nallanchakrava, Manoj Kumar Mallela, V Shiva Kumar Jeenepalli, H M Niharika

Affiliations

  1. Department of Pedodontics and Preventive Dentistry, Panineeya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.

PMID: 32189916 PMCID: PMC7069136 DOI: 10.4103/jomfp.JOMFP_35_20

Abstract

Neurofibromatosis type 1 (NF-1) or von Recklinghausen's disease is a rare genetic disorder characterized by the development of multiple noncancerous (benign) tumors of nerves and skin (neurofibromas). Head-and-neck neurofibroma is generally located in the soft tissue. Here, we present a case of a 12-year-old girl with NF-1. The disease started in childhood with the appearance of multiple hyperpigmented skin macules. The girl presents generalized freckling and café au lait spots throughout the body and a diffused swelling measuring about 4 cm × 3 cm, extending from the right maxillary hard palate region to the midpalate. The diagnosis of NF-1 was made according to the presence of two or more diagnostic criteria of the National Institute of Health Consensus Development Conference. No recurrence was observed in a 15-month follow-up after extensive surgical ablation.

Copyright: © 2020 Journal of Oral and Maxillofacial Pathology.

Keywords: Café au lait spots; S-100 protein; neurofibroma type 1; von Recklinghausen disease

Conflict of interest statement

There are no conflicts of interest.

References

  1. Ann Intern Med. 2006 Jun 6;144(11):842-9 - PubMed
  2. J Periodontol. 2006 Feb;77(2):310-5 - PubMed
  3. J Hist Neurosci. 2010 Oct;19(4):333-48 - PubMed
  4. Oral Surg Oral Med Oral Pathol. 1984 Oct;58(4):493-8 - PubMed
  5. J Indian Soc Pedod Prev Dent. 2009 Jan-Mar;27(1):62-4 - PubMed
  6. Oral Surg Oral Med Oral Pathol. 1991 Oct;72(4):456-61 - PubMed
  7. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997 Dec;84(6):595-7 - PubMed
  8. J Pediatr. 1997 Nov;131(5):678-82 - PubMed
  9. Indian J Dent Res. 2006 Jul-Sep;17(3):135-8 - PubMed
  10. J Med Genet. 2007 Feb;44(2):81-8 - PubMed
  11. Skeletal Radiol. 2000 Apr;29(4):224-6 - PubMed

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