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Sarveazad A, Babahajian A, Amini N, et al. Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and Meta-Analysis. Basic Clin Neurosci. 2019;10(5):419-431doi: 10.32598/bcn.9.10.290.
Sarveazad, A., Babahajian, A., Amini, N., Shamseddin, J., & Yousefifard, M. (2019). Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and Meta-Analysis. Basic and clinical neuroscience, 10(5), 419-431. https://doi.org/10.32598/bcn.9.10.290
Sarveazad, Arash, et al. "Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and Meta-Analysis." Basic and clinical neuroscience vol. 10,5 (2019): 419-431. doi: https://doi.org/10.32598/bcn.9.10.290
Sarveazad A, Babahajian A, Amini N, Shamseddin J, Yousefifard M. Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and Meta-Analysis. Basic Clin Neurosci. 2019 Sep-Oct;10(5):419-431. doi: 10.32598/bcn.9.10.290. Epub 2019 Sep 01. PMID: 32284831; PMCID: PMC7149953.
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Basic Clin Neurosci. 2019 Sep-Oct;10(5):419-431. doi: 10.32598/bcn.9.10.290. Epub 2019 Sep 01.

Posterior Tibial Nerve Stimulation in Fecal Incontinence: A Systematic Review and Meta-Analysis.

Basic and clinical neuroscience

Arash Sarveazad, Asrin Babahajian, Naser Amini, Jebreil Shamseddin, Mahmoud Yousefifard

Affiliations

  1. Colorectal Research Center, Iran University of Medical Sciences, Tehran, Iran.
  2. Liver and Digestive Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran.
  3. Cellular and Molecular Research Center, Iran University of Medical Sciences, Tehran, Iran.
  4. Molecular Medicine Research Center, Hormozgan Health Institute, Department of Parasitology, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
  5. Physiology Research Center, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.

PMID: 32284831 PMCID: PMC7149953 DOI: 10.32598/bcn.9.10.290

Abstract

INTRODUCTION: The present systematic review and meta-analysis aims to investigate the role of Posterior Tibial Nerve Stimulation (PTNS) in the control of Fecal Incontinence (FI).

METHODS: Two independent reviewers extensively searched in the electronic databases of Medline, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science, CINAHL, and Scopus for the studies published until the end of 2016. Only randomized clinical trials were included. The studied outcomes included FI episodes, FI score, resting pressure, squeezing pressure, and maximum tolerable pressure. The data were reported as Standardized Mean Differences (SMD) with 95% confidence interval.

RESULTS: Five articles were included in the present study (249 patients under treatment with PTNS and 239 in the sham group). Analyses showed that PTNS led to a significant decrease in the number of FI episodes (SMD=-0.38; 95% CI: -0.67-0.10; P=0.009). Yet, it did not have an effect on FI score (SMD=0.13; 95% CI: -0.49-0.75; P=0.68), resting pressure (SMD=0.12; 95% CI: -0.14-0.37; P=0.67), squeezing pressure (SMD=-0.27; 95% CI: -1.03-0.50; P=0.50), and maximum tolerable pressure (SMD=-0.10; 95% CI: -0.40-0.24; P=0.52).

CONCLUSION: Based on the results, it seems that the prescription of PTNS alone cannot significantly improve FI.

Copyright© 2019 Iranian Neuroscience Society.

Keywords: Electrical nerve stimulation; Fecal incontinence; Tibial nerve; Tibial neuromodulation

Conflict of interest statement

Conflict of interest The authors declared no conflict of interest.

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