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Perspect Med Virol. 2003;9:51-67. doi: 10.1016/S0168-7069(03)09004-9. Epub 2004 Sep 14.

I, 3. The enteric nervous system and infectious diarrhea.

Perspectives in medical virology

Ove Lundgren, Lennart Svensson

Affiliations

  1. Department of Physiology, Sahlgrenska Academy, Göteborg University, Box 432, S-405 30, Göteborg, Sweden.
  2. Department of Virology, Swedish Institute for Infectious Disease Control, S-171 82 Solna, Sweden.

PMID: 32287599 PMCID: PMC7133836 DOI: 10.1016/S0168-7069(03)09004-9

Abstract

This chapter discusses the background knowledge about the enteric nervous system (ENS) as well as the role of ENS in secretory states of the small intestine. The chapter describes the anatomy and physiology of the ENS. A description of the experimental evidence for the involvement of ENS in secretory states of the gut, primarily in cholera toxin-induced secretion that is the most thoroughly investigated secretory state, is presented in the chapter. The chapter focuses on the involvement of ENS in rotavirus (RV) diarrhea. The involvement of the ENS in diarrhea pathophysiology opens up new potential sites of action for drugs in the treatment of intestinal secretory states. The chapter concludes with a discussion of the sites of action for the pharmacological treatment of diarrhea.

Copyright © 2003 Published by Elsevier B.V.

References

  1. Acta Physiol Scand. 1997 Aug;160(4):379-86 - PubMed
  2. Science. 1996 Apr 5;272(5258):101-4 - PubMed
  3. Gastroenterology. 1989 Feb;96(2 Pt 1):368-76 - PubMed
  4. J Physiol. 1957 Jan 23;135(1):182-205 - PubMed
  5. Scand J Gastroenterol. 1983 May;18(4):537-43 - PubMed
  6. Acta Physiol Scand. 1991 May;142(1):127-32 - PubMed
  7. N Engl J Med. 2000 Aug 17;343(7):463-7 - PubMed
  8. Aliment Pharmacol Ther. 1999 Dec;13 Suppl 6:15-9 - PubMed
  9. Acta Physiol Scand Suppl. 1981;496:1-57 - PubMed
  10. Aliment Pharmacol Ther. 1999 Dec;13 Suppl 6:27-32 - PubMed
  11. Acta Physiol Scand. 1997 Aug;160(4):371-8 - PubMed
  12. Microbes Infect. 2001 Nov;3(13):1145-56 - PubMed
  13. Gut. 2000 Sep;47(3):382-6 - PubMed
  14. J Pharmacol Exp Ther. 1990 Sep;254(3):792-8 - PubMed
  15. Am J Physiol. 1997 Aug;273(2 Pt 1):G422-35 - PubMed
  16. N Engl J Med. 1968 Jul 25;279(4):176-81 - PubMed
  17. Gastroenterology. 1975 Aug;69(2):479-82 - PubMed
  18. Science. 2000 Jan 21;287(5452):491-5 - PubMed
  19. J Physiol. 1984 Jun;351:313-25 - PubMed
  20. Neuroscience. 1983 Mar;8(3):593-608 - PubMed
  21. Int J Antimicrob Agents. 2000 Feb;14(1):81-7 - PubMed
  22. J Physiol. 1986 Dec;381:465-82 - PubMed
  23. Acta Physiol Scand. 1996 Oct;158(2):115-8 - PubMed
  24. J Virol. 1994 Jan;68(1):251-7 - PubMed
  25. Acta Physiol Scand. 1988 Aug;133(4):551-7 - PubMed
  26. Scand J Gastroenterol. 1981 Apr;16(3):377-84 - PubMed
  27. Acta Physiol Scand. 1982 Apr;114(4):573-7 - PubMed
  28. Gastroenterology. 1993 Nov;105(5):1286-93 - PubMed
  29. Scand J Gastroenterol. 1982 Aug;17(5):695-703 - PubMed
  30. Br J Pharmacol. 1999 Jun;127(4):887-94 - PubMed
  31. Gastroenterology. 1986 Jul;91(1):225-41 - PubMed
  32. Acta Pathol Microbiol Immunol Scand A. 1984 Jan;92(1):15-21 - PubMed
  33. Neuroscience. 1980;5(1):1-20 - PubMed
  34. J Auton Nerv Syst. 1989 Mar;26(2):113-20 - PubMed
  35. Acta Physiol Scand. 1979 Nov;107(3):239-49 - PubMed
  36. Acta Physiol Scand Suppl. 1970;349:33-68 - PubMed
  37. J Clin Invest. 1997 Jul 1;100(1):6-10 - PubMed
  38. J Physiol. 1986 Sep;378:1-11 - PubMed
  39. Acta Physiol Scand. 1992 Jul;145(3):229-37 - PubMed
  40. J Neurosci. 1992 Jan;12(1):235-48 - PubMed
  41. Trends Neurosci. 1994 Aug;17(8):315-20 - PubMed
  42. Acta Physiol Scand. 1990 Jan;138(1):75-84 - PubMed
  43. J Comp Neurol. 1982 Sep 1;210(1):49-58 - PubMed
  44. J Auton Nerv Syst. 1988 Nov;25(1):1-13 - PubMed
  45. Gut. 1981 Nov;22(11):958-63 - PubMed
  46. Am J Physiol Gastrointest Liver Physiol. 2001 May;280(5):G787-94 - PubMed
  47. Gastroenterology. 1984 Aug;87(2):386-91 - PubMed
  48. Acta Physiol Scand. 1983 Feb;117(2):195-202 - PubMed
  49. Br Med Bull. 1979 Sep;35(3):263-8 - PubMed
  50. J Physiol. 1988 Apr;398:371-90 - PubMed

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