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Yu H, Fought EL, Windus TL, et al. Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction. ACS Omega. 2020;5(16):9311-9315doi: 10.1021/acsomega.0c00201.
Yu, H., Fought, E. L., Windus, T. L., & Kraus, G. A. (2020). Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction. ACS omega, 5(16), 9311-9315. https://doi.org/10.1021/acsomega.0c00201
Yu, Huangchao, et al. "Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction." ACS omega vol. 5,16 (2020): 9311-9315. doi: https://doi.org/10.1021/acsomega.0c00201
Yu H, Fought EL, Windus TL, Kraus GA. Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction. ACS Omega. 2020 Apr 17;5(16):9311-9315. doi: 10.1021/acsomega.0c00201. eCollection 2020 Apr 28. PMID: 32363281; PMCID: PMC7191567.
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ACS Omega. 2020 Apr 17;5(16):9311-9315. doi: 10.1021/acsomega.0c00201. eCollection 2020 Apr 28.

Direct Synthesis of the Phenanthroviridone Skeleton Using a Highly Regioselective Nitroquinone Diels-Alder Reaction.

ACS omega

Huangchao Yu, Ellie L Fought, Theresa L Windus, George A Kraus

Affiliations

  1. Department of Chemistry, Iowa State University, Ames, Iowa 50011, United States.

PMID: 32363281 PMCID: PMC7191567 DOI: 10.1021/acsomega.0c00201

Abstract

A variety of nucleophiles react efficiently with in situ generated nitroquinones. The reaction with substituted resorcinols led to the direct synthesis of the phenanthroviridinone and lagumycin skeleton via a highly regioselective Diels-Alder reaction.

Copyright © 2020 American Chemical Society.

Conflict of interest statement

The authors declare no competing financial interest.

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