Display options
Cite
Sandhu N, Navarro V. Drug-Induced Liver Injury in GI Practice. Hepatol Commun. 2020;4(5):631-645doi: 10.1002/hep4.1503.
Sandhu, N., & Navarro, V. (2020). Drug-Induced Liver Injury in GI Practice. Hepatology communications, 4(5), 631-645. https://doi.org/10.1002/hep4.1503
Sandhu, Naemat, and Navarro, Victor. "Drug-Induced Liver Injury in GI Practice." Hepatology communications vol. 4,5 (2020): 631-645. doi: https://doi.org/10.1002/hep4.1503
Sandhu N, Navarro V. Drug-Induced Liver Injury in GI Practice. Hepatol Commun. 2020 Mar 13;4(5):631-645. doi: 10.1002/hep4.1503. eCollection 2020 May. PMID: 32363315; PMCID: PMC7193133.
Copy Download .nbib Format: NLM
Share it on

Hepatol Commun. 2020 Mar 13;4(5):631-645. doi: 10.1002/hep4.1503. eCollection 2020 May.

Drug-Induced Liver Injury in GI Practice.

Hepatology communications

Naemat Sandhu, Victor Navarro

Affiliations

  1. Division of Digestive Diseases and Transplantation Albert Einstein Healthcare Network Philadelphia PA.

PMID: 32363315 PMCID: PMC7193133 DOI: 10.1002/hep4.1503

Abstract

Although drug-induced liver injury (DILI) is a rare clinical event, it carries significant morbidity and mortality, leaving it as the leading cause of acute liver failure in the United States. It is one of the most challenging diagnoses encountered by gastroenterologists. The development of various drug injury networks has played a vital role in expanding our knowledge regarding drug-related and herbal and dietary supplement-related liver injury. In this review, we discuss what defines liver injury, epidemiology of DILI, its biochemical and pathologic patterns, and management.

© 2020 The Authors. Hepatology Communications published by Wiley Periodicals, Inc., on behalf of the American Association for the Study of Liver Diseases.

References

  1. Bone Marrow Transplant. 2020 Mar;55(3):485-495 - PubMed
  2. Gastroenterology. 2013 Jun;144(7):1419-25, 1425.e1-3; quiz e19-20 - PubMed
  3. Atherosclerosis. 2006 Jan;184(1):233-4 - PubMed
  4. J Clin Gastroenterol. 2004 Oct;38(9):833 - PubMed
  5. Hepatology. 2009 Jun;49(6):2001-9 - PubMed
  6. Hepatol Res. 2003 Nov;27(3):192-195 - PubMed
  7. Am J Gastroenterol. 2016 Jul;111(7):958-65 - PubMed
  8. Annu Rev Pharmacol Toxicol. 2007;47:513-39 - PubMed
  9. Hepatology. 1997 Sep;26(3):664-9 - PubMed
  10. Perspect Biol Med. 1968 Autumn;12(1):135-61 - PubMed
  11. J Hepatol. 2009 Jan;50(1):111-7 - PubMed
  12. Hepatology. 2002 Aug;36(2):451-5 - PubMed
  13. J Hepatol. 2011 Apr;54(4):773-94 - PubMed
  14. J Clin Epidemiol. 1993 Nov;46(11):1323-30 - PubMed
  15. Dig Liver Dis. 2014 Dec;46(12):1116-20 - PubMed
  16. J Pharmacol Exp Ther. 1990 Dec;255(3):1377-84 - PubMed
  17. Clin Gastroenterol Hepatol. 2018 Sep;16(9):1495-1502 - PubMed
  18. J Nutr. 2011 Feb;141(2):261-6 - PubMed
  19. Lancet. 2010 Dec 4;376(9756):1916-22 - PubMed
  20. Biol Blood Marrow Transplant. 2009 Nov;15(11):1447-54 - PubMed
  21. Gastroenterology. 2015 Jun;148(7):1340-52.e7 - PubMed
  22. Gastroenterol Clin North Am. 2017 Jun;46(2):273-296 - PubMed
  23. Am J Med. 1965 Mar;38:359-77 - PubMed
  24. Liver Int. 2007 May;27(4):465-74 - PubMed
  25. Nat Rev Clin Oncol. 2016 Aug;13(8):473-86 - PubMed
  26. Liver Int. 2016 Apr;36(4):603-9 - PubMed
  27. Evid Based Complement Alternat Med. 2013;2013:938764 - PubMed
  28. Hepatology. 2008 Jun;47(6):2003-9 - PubMed
  29. J Clin Oncol. 2018 Jun 10;36(17):1714-1768 - PubMed
  30. Scand J Gastroenterol. 2005 Sep;40(9):1095-101 - PubMed
  31. Drug Saf. 2001;24(7):483-90 - PubMed
  32. Arch Pediatr Adolesc Med. 2007 Oct;161(10):978-85 - PubMed
  33. Drug Saf. 2009;32(1):55-68 - PubMed
  34. Hepatology. 2013 Jul;58(1):388-96 - PubMed
  35. Dig Dis Sci. 1997 Jul;42(7):1486-8 - PubMed
  36. J Hepatol. 2019 Jun;70(6):1222-1261 - PubMed
  37. Hepatology. 2014 Feb;59(2):661-70 - PubMed
  38. Leg Med (Tokyo). 2007 Sep;9(5):258-64 - PubMed
  39. Gastroenterology. 1975 Aug;69(2):289-302 - PubMed
  40. Br J Clin Pharmacol. 2004 Jul;58(1):71-80 - PubMed
  41. Hepatology. 2010 Dec;52(6):2065-76 - PubMed
  42. Hepatology. 2006 Dec;44(6):1581-8 - PubMed
  43. Clin Liver Dis. 2017 Feb;21(1):21-34 - PubMed
  44. US Gastroenterol Hepatol Rev. 2010 Jan 1;6:73-80 - PubMed
  45. Hepatology. 2014 Feb;59(2):612-21 - PubMed
  46. Gastroenterology. 2005 Aug;129(2):512-21 - PubMed
  47. Drug Saf. 2017 Sep;40(9):783-787 - PubMed
  48. Hepatology. 2010 Jun;51(6):2040-8 - PubMed
  49. Immunol Rev. 2000 Apr;174:21-34 - PubMed
  50. Aliment Pharmacol Ther. 2007 Jun 15;25(12):1411-21 - PubMed
  51. Aliment Pharmacol Ther. 2006 Jun 1;23(11):1643-7 - PubMed
  52. Gastroenterology. 2014 Jul;147(1):96-108.e4 - PubMed
  53. Am J Epidemiol. 2004 Aug 15;160(4):339-49 - PubMed
  54. Gastroenterol Hepatol (N Y). 2013 Oct;9(10):633-9 - PubMed
  55. Am J Health Syst Pharm. 2000 May 15;57(10):963-9 - PubMed
  56. Endocr Pract. 2002 May-Jun;8(3):222-4 - PubMed
  57. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3592-7 - PubMed
  58. Gastroenterology. 2008 Dec;135(6):1924-34, 1934.e1-4 - PubMed
  59. J Clin Epidemiol. 1993 Nov;46(11):1331-6 - PubMed
  60. Semin Arthritis Rheum. 2016 Oct;46(2):253-258 - PubMed
  61. J Pharmacol Exp Ther. 1996 Sep;278(3):1000-5 - PubMed
  62. Nature. 1967 Aug 12;215(5102):744-5 - PubMed
  63. J Clin Lipidol. 2012 Jul-Aug;6(4):340-51 - PubMed
  64. Clin Liver Dis. 2013 Nov;17(4):587-607, viii - PubMed
  65. Ann Intern Med. 2002 Dec 17;137(12):947-54 - PubMed
  66. Gastroenterology. 2014 Jul;147(1):109-118.e5 - PubMed
  67. Front Pharmacol. 2019 Jul 19;10:816 - PubMed
  68. Gastroenterology. 2009 Sep;137(3):856-64, 864.e1 - PubMed
  69. Clin Pharmacol Ther. 2011 Jun;89(6):806-15 - PubMed
  70. Semin Liver Dis. 2014 May;34(2):194-204 - PubMed
  71. Hepatology. 2014 Oct;60(4):1399-408 - PubMed
  72. Hepatology. 2017 Jan;65(1):363-373 - PubMed
  73. Hepatology. 2017 Apr;65(4):1267-1277 - PubMed
  74. J Hepatol. 2005 Jun;42(6):944-6 - PubMed
  75. Liver Int. 2018 Feb;38(2):198-209 - PubMed
  76. Dig Dis Sci. 1983 Aug;28(8):673-83 - PubMed
  77. Anesth Analg. 2002 Feb;94(2):243-9, table of contents - PubMed
  78. Int J Mol Sci. 2016 Feb 29;17(3):313 - PubMed
  79. N Engl J Med. 2015 Jul 2;373(1):23-34 - PubMed
  80. Front Pharmacol. 2019 Jul 23;10:730 - PubMed
  81. J Clin Gastroenterol. 2017 Jan;51(1):63-69 - PubMed
  82. Toxicol Lett. 1998 Sep 1;98(1-2):41-50 - PubMed
  83. Aliment Pharmacol Ther. 2006 Oct 15;24(8):1187-95 - PubMed
  84. J Hepatol. 2017 Jul;67(1):137-144 - PubMed
  85. Int J Mol Sci. 2015 Dec 24;17(1): - PubMed
  86. Curr Opin Gastroenterol. 2010 May;26(3):222-6 - PubMed
  87. Med Hypotheses. 2016 Aug;93:150-3 - PubMed
  88. Acta Gastroenterol Belg. 1995 May-Aug;58(3-4):290-6 - PubMed
  89. Am J Gastroenterol. 2017 Sep;112(9):1382-1388 - PubMed
  90. Gut. 2017 Jun;66(6):1154-1164 - PubMed
  91. Clin Gastroenterol Hepatol. 2007 Jul;5(7):809-12 - PubMed
  92. Alcohol Clin Exp Res. 1986 Jan-Feb;10(1):3-15 - PubMed
  93. Hepatology. 2010 Jun;51(6):2117-26 - PubMed
  94. Int J Cancer. 2017 Sep 1;141(5):1018-1028 - PubMed
  95. Cancer Prev Res (Phila). 2017 Oct;10(10):571-579 - PubMed
  96. Chem Biol Interact. 2001 Sep 28;137(3):203-12 - PubMed
  97. Dig Liver Dis. 2019 Aug;51(8):1074-1078 - PubMed
  98. Clin Toxicol (Phila). 2009 Feb;47(2):101-11 - PubMed
  99. Chem Res Toxicol. 2008 Jan;21(1):84-92 - PubMed
  100. Gastroenterology. 2011 Jul;141(1):338-47 - PubMed
  101. Nat Genet. 2009 Jul;41(7):816-9 - PubMed
  102. Gastroenterology. 2019 Jun;156(8):2230-2241.e11 - PubMed
  103. JAMA. 2016 Oct 11;316(14):1464-1474 - PubMed
  104. Transl Gastroenterol Hepatol. 2017 Dec 19;2:114 - PubMed
  105. J Clin Gastroenterol. 2009 Aug;43(7):672-5 - PubMed
  106. Liver Int. 2016 Feb;36(2):158-65 - PubMed

Publication Types