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Int J Inflam. 2020 Apr 28;2020:6492720. doi: 10.1155/2020/6492720. eCollection 2020.

Evaluation of Inflammatory Markers in Patients Undergoing a Short-Term Aerobic Exercise Program while Hospitalized due to Acute Exacerbation of COPD.

International journal of inflammation

Caroline Knaut, Carolina Bonfanti Mesquita, Victor Zuniga Dourado, Irma de Godoy, Suzana E Tanni

Affiliations

  1. UNESP-Univ Estadual Paulista, Campus de Botucatu, Department of Internal Medicine, Pneumology Area, SP, Brazil.

PMID: 32411343 PMCID: PMC7204117 DOI: 10.1155/2020/6492720

Abstract

INTRODUCTION: Acute exacerbation is an important factor for a worse prognosis in patients with chronic obstructive pulmonary disease (COPD). It promotes the increase of the inflammatory process and worsens quality of life, lung function, and muscle weakness. It is believed that physical exercise performed during the exacerbation breaks the vicious cycle of systemic manifestations without an increase in the inflammatory process.

OBJECTIVE: To evaluate the influence of short-term aerobic physical exercise during hospitalization on inflammatory markers.

RESULTS: Patients of both groups did not differ in severity of disease and general characteristics. The intervention group did not show worsening in the inflammatory process after aerobic activity: TNF-

CONCLUSION: The present study showed that the aerobic physical activity initiated during hospitalization in patients with exacerbated COPD did not worsen the inflammatory process.

Copyright © 2020 Caroline Knaut et al.

Conflict of interest statement

The authors declare that they have no conflicts of interest.

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