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J Menopausal Med. 2020 Apr;26(1):18-23. doi: 10.6118/jmm.19004.

Age of Natural Menopause and Related Factors among the Tabari Cohort.

Journal of menopausal medicine

Marzieh Zamaniyan, Mahmood Moosazadeh, Sepideh Peyvandi, Kaveh Jaefari, Reza Goudarzi, Mahdi Moradinazar, Motahareh Kheradmand

Affiliations

  1. Diabetes Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
  2. Infertility Center, Department of Obstetrics and Gynecology, Mazandaran University of Medical Sciences, Sari, Iran.
  3. Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran.
  4. Mazandaran Heart Center, Mazandaran University of Medical Sciences, Sari, Iran.
  5. Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran.
  6. Research Center for Environmental Determinants of Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
  7. Health Sciences Research Center, Addiction Institute, Mazandaran University of Medical Sciences, Sari, Iran. [email protected].

PMID: 32307946 PMCID: PMC7160589 DOI: 10.6118/jmm.19004

Abstract

OBJECTIVES: The age of menopause is affected by several factors. In this study we aimed to identify the age of natural menopause and its related factors in a large-scale population-based cohort in Iran.

METHODS: In this study, a subset of data collected during the enrollment phase of the Tabari cohort study was utilized. Reproductive history and other related data were collected using a structured questionnaire. Blood samples were obtained from all participants. Data were analyzed using chi-square test, independent t test, and ANOVA as well as a multivariate linear regression model.

RESULTS: Among participants of the Tabari cohort, 2,753 were menopausal women. The mean age of natural and induced menopause was 49.2 ± 4.7 and 43.2 ± 6.4 years, respectively (

CONCLUSIONS: The age of natural menopause in this study was similar to that in other studies, and the number of pregnancies was positively associated with the age of menopause after adjustments for confounding variables.

Copyright © 2020 by The Korean Society of Menopause.

Keywords: Menopause; Natural fertility; Pre-menopause; Tabari cohort study

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

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