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Zhvania MG, Bikashvili TZ, Japaridze NJ, et al. White noise and neuronal porosome complex: transmission electron microscopic study. Discoveries (Craiova). 2014;2(3):e25doi: 10.15190/d.2014.17.
Zhvania, M. G., Bikashvili, T. Z., Japaridze, N. J., Lazrishvili, I. I., & Ksovreli, M. (2014). White noise and neuronal porosome complex: transmission electron microscopic study. Discoveries (Craiova, Romania), 2(3), e25. https://doi.org/10.15190/d.2014.17
Zhvania, Mzia G, et al. "White noise and neuronal porosome complex: transmission electron microscopic study." Discoveries (Craiova, Romania) vol. 2,3 (2014): e25. doi: https://doi.org/10.15190/d.2014.17
Zhvania MG, Bikashvili TZ, Japaridze NJ, Lazrishvili II, Ksovreli M. White noise and neuronal porosome complex: transmission electron microscopic study. Discoveries (Craiova). 2014 Aug 19;2(3):e25. doi: 10.15190/d.2014.17. PMID: 32309553; PMCID: PMC6941563.
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Discoveries (Craiova). 2014 Aug 19;2(3):e25. doi: 10.15190/d.2014.17.

White noise and neuronal porosome complex: transmission electron microscopic study.

Discoveries (Craiova, Romania)

Mzia G Zhvania, Tamar Z Bikashvili, Nadezhda J Japaridze, Ilia I Lazrishvili, Mariam Ksovreli

Affiliations

  1. Institute of Chemical Biology, Ilia State University, 3/5 K. Cholokashvili Avenue, 0162 Tbilisi, Georgia.
  2. I. Beritashvili Center of Experimental Biomedicine, 14 Gotua Street, 0160 Tbilisi, Georgia.
  3. New Vision University, 1a, Mikeladze Street, 0159 Tbilisi, Georgia.

PMID: 32309553 PMCID: PMC6941563 DOI: 10.15190/d.2014.17

Abstract

In the present electron microscopic study the effect of continuous white noise on the morphology of synapses and neuronal porosome complex (the neurotransmitter-release or secretory machinery) in two subcortical auditory brain regions - colliculus inferior and medial geniculate body in cat, were investigated. Several morphological alterations in some synapses were detected in both subcortical areas. These alterations mainly indicate to the decrease of functional activity of synapses. Rarely important pathological modifications in pre- and post-synaptic regions were detected. In addition to descriptive studies, the morphometric analysis of porosome diameter and depth was performed in colliculus inferior and medial geniculate body. The results revealed that while white noise has no effect on the porosome diameter and depth in colliculus inferior, it provokes significant alterations in the morphology of porosome complex in medial geniculate body. In particular, the significant increase of porosome depth in this nucleus may reflect the alteration in neurotransmission.

Copyright © 2014, Applied Systems.

Keywords: colliculus inferior; medial geniculate body; ultrastructure of porosome; ultrastructure of synapses; white noise

Conflict of interest statement

Conflict of interests: Authors declare no conflict of interests.

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