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Saravanan S, Umapathi V, Priyanka M, et al. Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus. Vet World. 2020;13(3):426-432doi: 10.14202/vetworld.2020.426-432.
Saravanan, S., Umapathi, V., Priyanka, M., Hosamani, M., Sreenivasa, B. P., Patel, B. H. M., Narayanan, K., Sanyal, A., & Basagoudanavar, S. H. (2020). Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus. Veterinary world, 13(3), 426-432. https://doi.org/10.14202/vetworld.2020.426-432
Saravanan, S, et al. "Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus." Veterinary world vol. 13,3 (2020): 426-432. doi: https://doi.org/10.14202/vetworld.2020.426-432
Saravanan S, Umapathi V, Priyanka M, Hosamani M, Sreenivasa BP, Patel BHM, Narayanan K, Sanyal A, Basagoudanavar SH. Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus. Vet World. 2020 Mar;13(3):426-432. doi: 10.14202/vetworld.2020.426-432. Epub 2020 Mar 09. PMID: 32367945; PMCID: PMC7183469.
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Vet World. 2020 Mar;13(3):426-432. doi: 10.14202/vetworld.2020.426-432. Epub 2020 Mar 09.

Hematological and serum biochemical profile in cattle experimentally infected with foot-and-mouth disease virus.

Veterinary world

S Saravanan, V Umapathi, M Priyanka, M Hosamani, B P Sreenivasa, B H M Patel, K Narayanan, Aniket Sanyal, S H Basagoudanavar

Affiliations

  1. Indian Council of Agricultural Research-Indian Veterinary Research Institute, Bengaluru, Karnataka, India.

PMID: 32367945 PMCID: PMC7183469 DOI: 10.14202/vetworld.2020.426-432

Abstract

BACKGROUND AND AIM: Foot-and-mouth disease (FMD) is an acute viral infection affecting cloven-hoofed animals causing vesicular erosions in the oral cavity and interdigital space. The present study was undertaken to ascertain the time-dependent changes in clinical, hematological, and biochemical profiles in different breeds of cattle following experimental infection.

MATERIALS AND METHODS: The animals were inoculated with 1.0×10

RESULTS: The white blood cell count declined sharply on days 7-13 and recovered on day 14 post-FMD infection. Biochemical analysis of serum markers for vital organ profile revealed no marked damage. However, a significant increase in blood urea nitrogen (BUN) value indicated pre-renal azotemia. Transient hyperthyroidism was indicated by the rise in T3 and T4 that can be correlated with a decrease in triglyceride and total cholesterol levels. In the cardiac damage assessment study, a distinct breed difference was observed wherein Malnad Gidda calves showed no cardiac damage.

CONCLUSION: Except thyroid profile, BUN, and creatine kinase-myocardial band, all other serum biochemical parameters showed no significant abnormalities, whereas lymphopenia is the only hematological change and it is suggested that effective ameliorative measures should be targeted mainly on the feed/water intake, thyroid gland, and the level of lymphocytes.

Copyright: © Saravanan, et al.

Keywords: biochemical profile; experimentally infected indigenous and crossbred calves; foot-and-mouth disease; hematological profile

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