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Ballatore Z, Bracci R, Maccaroni E, et al. Expectations and psychological issues before genetic counseling: analysis of distress determinant factors. Hered Cancer Clin Pract. 2020;18:10doi: 10.1186/s13053-020-00142-1.
Ballatore, Z., Bracci, R., Maccaroni, E., Svarca, L., Bianchi, F., Belvederesi, L., Bruciati, C., Pagliaretta, S., Murrone, A., Bini, F., Pistelli, M., Ricci, G., & Berardi, R. (2020). Expectations and psychological issues before genetic counseling: analysis of distress determinant factors. Hereditary cancer in clinical practice, 1810. https://doi.org/10.1186/s13053-020-00142-1
Ballatore, Zelmira, et al. "Expectations and psychological issues before genetic counseling: analysis of distress determinant factors." Hereditary cancer in clinical practice vol. 18 (2020): 10. doi: https://doi.org/10.1186/s13053-020-00142-1
Ballatore Z, Bracci R, Maccaroni E, Svarca L, Bianchi F, Belvederesi L, Bruciati C, Pagliaretta S, Murrone A, Bini F, Pistelli M, Ricci G, Berardi R. Expectations and psychological issues before genetic counseling: analysis of distress determinant factors. Hered Cancer Clin Pract. 2020 Apr 29;18:10. doi: 10.1186/s13053-020-00142-1. eCollection 2020. PMID: 32368313; PMCID: PMC7189592.
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Hered Cancer Clin Pract. 2020 Apr 29;18:10. doi: 10.1186/s13053-020-00142-1. eCollection 2020.

Expectations and psychological issues before genetic counseling: analysis of distress determinant factors.

Hereditary cancer in clinical practice

Zelmira Ballatore, Raffaella Bracci, Elena Maccaroni, Lucia Svarca, Francesca Bianchi, Laura Belvederesi, Cristiana Bruciati, Silvia Pagliaretta, Alberto Murrone, Federica Bini, Mirco Pistelli, Giulia Ricci, Rossana Berardi

Affiliations

  1. 1Clinica Oncologica, Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona Umberto I G M Lancisi G Salesi, Ancona, Italy.
  2. 2Oncologia, Azienda Ospedaliera Ospedali Riuniti Marche Nord, Presidio Santa Croce, Fano, Italy.
  3. 3Neuropsichiatria Infantile, Azienda Ospedaliero Universitaria Ospedali Riuniti di Ancona Umberto I G M Lancisi G Salesi, Ancona, Italy.

PMID: 32368313 PMCID: PMC7189592 DOI: 10.1186/s13053-020-00142-1

Abstract

BACKGROUND: Hereditary non-polyposis colorectal cancer (HNPCC) and Hereditary Breast and Ovarian Cancer Syndrome (HBOC) are the most common hereditary cancer syndromes in which a genetic test is available. Potential risks associated with testing include psychological harm, emotional distress and insurance problems.

METHODS: The aim of the present study is to investigate determinants of distress in a sample of Italian subjects undergoing genetic counseling. Demographic information and psychological distress were assessed by using a self-reported questionnaire and the "Hospital Anxiety and Depression Scale" (HAD), before attending the first counseling session.

RESULTS: Of the all subjects referred for the first time to our Center (January 2012-June 2013), a total of 227 were eligible (female/male = 174/53) for the survey, 134 (59%) were oncologic patients and of these, 116 received genetic test (36 for HNPCC and 80 for HBOC). The remaining 93 (41%) were healthy subjects referred for suspected familiar history and of this group, 65 subjects performed predictive test in a family with a known pathogenic mutation (53 for HBOC and 12 for HNPCC). Affected subjects had a significantly higher level of anxiety (

CONCLUSIONS: Greater level of distress identified on females, single and younger subjects.

© The Author(s) 2020.

Keywords: Genetic counseling; Genetic test; HBOC; HNPCC; Psychological distress

Conflict of interest statement

Competing interestsThe authors declare that they have no competing interests.

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