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Front Genet. 2020 May 12;11:459. doi: 10.3389/fgene.2020.00459. eCollection 2020.

Genomic and Phenotypic Heterogeneity of Clinical Isolates of the Human Pathogens .

Frontiers in genetics

Renato A C Dos Santos, Jacob L Steenwyk, Olga Rivero-Menendez, Matthew E Mead, Lilian P Silva, Rafael W Bastos, Ana Alastruey-Izquierdo, Gustavo H Goldman, Antonis Rokas

Affiliations

  1. Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil.
  2. Department of Biological Sciences, Vanderbilt University, Nashville, TN, United States.
  3. Medical Mycology Reference Laboratory, National Center for Microbiology, Instituto de Salud Carlos III, Madrid, Spain.

PMID: 32477406 PMCID: PMC7236307 DOI: 10.3389/fgene.2020.00459

Abstract

Fungal pathogens are a global threat to human health. For example, fungi from the genus

Copyright © 2020 dos Santos, Steenwyk, Rivero-Menendez, Mead, Silva, Bastos, Alastruey-Izquierdo, Goldman and Rokas.

Keywords: Aspergillus; antifungal drug susceptibility; cryptic species; drug resistance; genetic determinants of virulence; genomics; strain heterogeneity; virulence

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