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Clin Case Rep. 2020 Feb 11;8(5):785-789. doi: 10.1002/ccr3.2703. eCollection 2020 May.

Molar and nonmolar triploidy: Recurrence or bad luck.

Clinical case reports

Brianne Robinson, Jo-Ann Brock, Craig Midgen, Jillian Coolen

Affiliations

  1. Dalhousie Medical School Halifax NS Canada.
  2. Departments of Anatomic Pathology and Obstetrics and Gynaecology Dalhousie University Halifax NS Canada.
  3. Department of Anatomic Pathology Dalhousie University Halifax NS Canada.
  4. Department of Obstetrics and Gynaecology Dalhousie University Halifax NS Canada.

PMID: 32477517 PMCID: PMC7250987 DOI: 10.1002/ccr3.2703

Abstract

In triploid pregnancies, the parental origin of the extra genome determines the phenotype and placental and fetal outcomes. Molecular genetics and placental pathology enable differentiation of molar vs nonmolar pregnancy to guide future planning.

© 2020 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Keywords: genomic imprinting; hydatidiform mole; triploidy

Conflict of interest statement

The authors of this study have no conflicts of interest to declare.

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