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Ebersole J, Samburova V, Son Y, et al. Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity. Tob Induc Dis. 2020;18:41doi: 10.18332/tid/116988.
Ebersole, J., Samburova, V., Son, Y., Cappelli, D., Demopoulos, C., Capurro, A., Pinto, A., Chrzan, B., Kingsley, K., Howard, K., Clark, N., & Khlystov, A. (2020). Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity. Tobacco induced diseases, 1841. https://doi.org/10.18332/tid/116988
Ebersole, Jeffrey, et al. "Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity." Tobacco induced diseases vol. 18 (2020): 41. doi: https://doi.org/10.18332/tid/116988
Ebersole J, Samburova V, Son Y, Cappelli D, Demopoulos C, Capurro A, Pinto A, Chrzan B, Kingsley K, Howard K, Clark N, Khlystov A. Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity. Tob Induc Dis. 2020 May 08;18:41. doi: 10.18332/tid/116988. eCollection 2020. PMID: 32435175; PMCID: PMC7233525.
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Tob Induc Dis. 2020 May 08;18:41. doi: 10.18332/tid/116988. eCollection 2020.

Harmful chemicals emitted from electronic cigarettes and potential deleterious effects in the oral cavity.

Tobacco induced diseases

Jeffrey Ebersole, Vera Samburova, Yeongkwon Son, David Cappelli, Christina Demopoulos, Antonina Capurro, Andres Pinto, Brian Chrzan, Karl Kingsley, Katherine Howard, Nathaniel Clark, Andrey Khlystov

Affiliations

  1. Department of Biomedical Sciences, School of Dental Medicine, University of Nevada Las Vegas, Las Vegas, United States.
  2. Organic Analytical Laboratory, Division of Atmospheric Sciences, Desert Research Institute, Reno, United States.
  3. Oral and Maxillofacial Medicine and Diagnostic Sciences, School of Dental Medicine, Case Western University, Cleveland, United States.

PMID: 32435175 PMCID: PMC7233525 DOI: 10.18332/tid/116988

Abstract

Use of electronic nicotine delivery systems (ENDS), such as electronic cigarettes (e-cigs), is increasing across the US population and is particularly troubling due to their adoption by adolescents, teens, and young adults. The industry's marketing approach for these instruments of addiction has been to promote them as a safer alternative to tobacco, a behavioral choice supporting smoking cessation, and as the 'cool' appearance of vaping with flavored products (e.g. tutti frutti, bubble gum, and buttered popcorn etc.). Thus, there is a clear need to better document the health outcomes of e-cig use in the oral cavity of the addicted chronic user. There appears to be an array of environmental toxins in the vapors, including reactive aldehydes and carbonyls resulting from the heating elements action on fluid components, as well as from the composition of chemical flavoring agents. The chemistry of these systems shows that the released vapors from the e-cigs frequently contain levels of environmental toxins that considerably exceed federal occupational exposure limits. Additionally, the toxicants in the vapors appear to be retained in the host fluids/tissues at levels often approximating 90% of the levels in the e-cig vapors. These water-soluble reactive toxins can challenge the oral cavity constituents, potentially contributing to alterations in the autochthonous microbiome and host cells critical for maintaining oral homeostasis. This review updates the existing chemistry/environmental aspects of e-cigs, as well as providing an overview of the somewhat limited data on potential oral health effects that could occur across the lifetime of daily e-cig users.

© 2020 Ebersole J. et al.

Keywords: e-cigarette; electronic nicotine delivery systems; oral health; public health; vaping

Conflict of interest statement

The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none was reported.

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