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Saudi J Biol Sci. 2020 Jun;27(6):1609-1623. doi: 10.1016/j.sjbs.2020.02.009. Epub 2020 Feb 17.

Molecular cloning and in-depth bioinformatics analysis of type II ribosome-inactivating protein isolated from .

Saudi journal of biological sciences

Masoumeh Rezaei-Moshaei, Ali Bandehagh, Ali Dehestani, Ali Pakdin-Parizi, Majid Golkar

Affiliations

  1. Department of Plant Breeding and Biotechnology, University of Tabriz, Tabriz, Iran.
  2. Genetics and Agricultural Biotechnology Institute of Tabarestan, Sari Agricultural Sciences and Natural Resources University, Sari, Iran.
  3. Pasteur Institute of Iran, Tehran, Iran.

PMID: 32489302 PMCID: PMC7253926 DOI: 10.1016/j.sjbs.2020.02.009

Abstract

Plant ribosome-inactivating proteins (RIPs) are N-glycosidases which inhibit protein synthesis through depurination of the ribosomal RNA sequence. Type II RIPs are heterodimer proteins which can bind to cell surfaces. The cytotoxicity of these RIPs is different.

© 2020 The Author(s).

Keywords: Physicochemical properties; Protein modeling; Recombinant RIP

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