Display options
Cite
Bahoush G, Vafapour M, Kariminejad R. New translocation in acute myeloid leukemia M4 eos. Leuk Res Rep. 2020;14:100209doi: 10.1016/j.lrr.2020.100209.
Bahoush, G., Vafapour, M., & Kariminejad, R. (2020). New translocation in acute myeloid leukemia M4 eos. Leukemia research reports, 14100209. https://doi.org/10.1016/j.lrr.2020.100209
Bahoush, Gholamreza, et al. "New translocation in acute myeloid leukemia M4 eos." Leukemia research reports vol. 14 (2020): 100209. doi: https://doi.org/10.1016/j.lrr.2020.100209
Bahoush G, Vafapour M, Kariminejad R. New translocation in acute myeloid leukemia M4 eos. Leuk Res Rep. 2020 Jun 08;14:100209. doi: 10.1016/j.lrr.2020.100209. eCollection 2020. PMID: 32566479; PMCID: PMC7296338.
Copy Download .nbib Format: NLM
Share it on

Leuk Res Rep. 2020 Jun 08;14:100209. doi: 10.1016/j.lrr.2020.100209. eCollection 2020.

New translocation in acute myeloid leukemia M4 eos.

Leukemia research reports

Gholamreza Bahoush, Maryam Vafapour, Roxana Kariminejad

Affiliations

  1. Associate Professor in Pediatrics, Pediatric Hematologist and Oncologist, Ali-Asghar Children Hospital, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  2. Chief resident of Pediatrics, Ali-Asghar Children Hospital, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
  3. Cytogenetic division, Kariminejad,Najmabadi Pathology & Genetics Center, Tehran, Iran.

PMID: 32566479 PMCID: PMC7296338 DOI: 10.1016/j.lrr.2020.100209

Abstract

The most common childhood malignancy is acute leukemia. Approximately 15- 20% of it, is Acute myeloid leukemia (AML). The general symptoms of this malignancy include fatigue, weakness, fever, paleness and bleeding disorders. There are two methods of classifying for AML: The French-American-British (FAB) and the World Health Organization (WHO) classification.The M4 eos subtype, also called myelomonocytic leukemia, is one subtype of AML with eosinophilia. The most common cytogenetic variations in this leukemia include inv (16) (p13q22) or the variant t (16; 16) (p13; q22). In this report, we present the first AML-M4 eos case with a new translocation that has not yet been reported.

© 2020 Published by Elsevier Ltd.

Keywords: AML M4, Eosinophilia; Acute myelomonocytic leukemia; Chromosomal translocation; ETV6-JAK2

Conflict of interest statement

None

References

  1. Curr Treat Options Oncol. 2008 Feb;9(1):95-105 - PubMed
  2. Blood. 2010 Jan 21;115(3):453-74 - PubMed
  3. Science. 1997 Nov 14;278(5341):1309-12 - PubMed
  4. Am J Med Genet. 2002 Oct 30;115(3):130-41 - PubMed
  5. Mol Cytogenet. 2013 May 05;6(1):18 - PubMed
  6. Blood. 1997 Oct 1;90(7):2535-40 - PubMed
  7. Blood. 1996 Mar 15;87(6):2459-63 - PubMed
  8. Haematologica. 2012 Dec;97(12):1783-5 - PubMed
  9. Blood. 2002 Dec 15;100(13):4325-36 - PubMed
  10. Mod Pathol. 2019 Apr;32(4):490-498 - PubMed
  11. Br J Haematol. 2014 Sep;166(6):809-17 - PubMed
  12. Blood. 1986 Dec;68(6):1242-9 - PubMed

Publication Types