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Int J Environ Res Public Health. 2020 May 25;17(10). doi: 10.3390/ijerph17103738.

Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis.

International journal of environmental research and public health

Vincenza Gianfredi, Lorenzo Blandi, Stefano Cacitti, Mirko Minelli, Carlo Signorelli, Andrea Amerio, Anna Odone

Affiliations

  1. School of Medicine, Vita-Salute San Raffaele University, 20132 Milan, Italy.
  2. Accademia Lombarda di Sanità Pubblica, Consorzio Pavese Studi Post-Universitari, Unit of Forensic Medicine and Forensic Sciences, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.
  3. CAPHRI Care and Public Health Research Institute, Maastricht University, 6211 Maastricht, The Netherlands.
  4. Unit of Forensic Medicine and Forensic Sciences, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, 27100 Pavia, Italy.
  5. Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DINOGMI), Section of Psychiatry, University of Genoa, 16132 Genoa, Italy.
  6. IRCCS Ospedale Policlinico San Martino, 16132 Genoa, Italy.
  7. Mood Disorders Program, Tufts Medical Center, Boston, MA 02111, USA.

PMID: 32466242 PMCID: PMC7277615 DOI: 10.3390/ijerph17103738

Abstract

Depression is a major contributor to the overall global burden of disease, with high prevalence and relapse rate. Several factors have been considered in order to reduce the depression burden. Among them, physical activity (PA) showed a potential protective role. However, evidence is contrasting probably because of the differences in PA measurement. The aim of this systematic review with meta-analysis is to assess the association between objectively measured PA and incident and prevalent depression. The systematic review was conducted according to methods recommended by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant papers published through 31 August 2019 were identified searching through the electronic databases PubMed/MEDLINE, Excerpta Medica dataBASE (Embase), PsycINFO, Scopus, Web of Science (WoS), and the Cochrane Library. All analyses were conducted using ProMeta3. Finally, 42 studies met inclusion criteria. The overall Effect size (ES) of depression for the highest vs. the lowest level of PA was -1.16 [(95% CI = -1.41; -0.91),

Keywords: accelerometer; depression; depressive symptoms; meta-analysis; objectively measure; physical activity

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