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Antioxidants (Basel). 2020 Jun 02;9(6). doi: 10.3390/antiox9060478.

Anthocyanins in Blueberries Grown in Hot Climate Exert Strong Antioxidant Activity and May Be Effective against Urinary Tract Bacteria.

Antioxidants (Basel, Switzerland)

Ana B Cerezo, Giorgiana M Cătunescu, Mercedes Martínez-Pais González, Ruth Hornedo-Ortega, Carmen R Pop, Crina Claudia Rusu, Flore Chirilă, Ancuța M Rotar, M Carmen Garcia-Parrilla, Ana M Troncoso

Affiliations

  1. Departamento de Nutrición y Bromatología, Toxicología y Medicina Legal, Facultad de Farmacia, Universidad de Sevilla, C/Profesor García González 2, 41012 Sevilla, Spain.
  2. Department of Technical and Soil Sciences, Faculty of Agriculture, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea M?n??tur 3-5, 400372 Cluj-Napoca, Romania.
  3. Axe Molécules d'Intérêt Biologique (MIB), Unité de Recherche Œnologie, EA4577, USC 1366 Institut National de la Recherche Agronomique (INRA), Institut des Sciences de la Vigne et du Vin (ISVV), Université de Bordeaux, 33882 Bordeaux, France.
  4. Department of Food Science, Faculty of Food Science and Technology, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea M?n??tur 3-5, 400372 Cluj-Napoca, Romania.
  5. Department of Nephrology, University of Medicine and Pharmacy "Iuliu Hatieganu", Victor Babe? 8, 400012 Cluj-Napoca, Romania.
  6. Department of Clinical and Paraclinical Sciences, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, Calea M?n??tur 3-5, 400372 Cluj-Napoca, Romania.

PMID: 32498420 PMCID: PMC7346222 DOI: 10.3390/antiox9060478

Abstract

Anthocyanins are extensively studied for their health-related properties, including antibacterial activity against urinary tract infections (UTI). Among common fruits, blueberries, with their remarkable antioxidant capacity, are one of the richest sources. Anthocyanin-rich extracts were obtained from four varieties: Snowchaser, Star, Stella Blue and Cristina Blue, grown in the hot climate of Southern Spain. Their total anthocyanins contents (TAC) were determined spectrophotometrically, and the anthocyanin profile by ultra high performance liquid chromatography - tandem mass spectrometer (UHPLC-MS/MS). Their antioxidant activity was assessed by oxygen radical absorbance capacity (ORAC) assay, while antibacterial activity against strains isolated from UTI patients was assessed in vitro, helping to select the varieties with the highest bioactive potential. Star showed the highest TAC and antioxidant activity (1663 ± 159 mg of cyanidin-3-

Keywords: Escherichia coli; Klebsiella pneumoniae; Micrococcus; ORAC; Providencia stuartii; Pseudomonas aeruginosa; UHPLC-MS/MS Orbitrap; antibacterial activity; cyanidin-3-rutinoside

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