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medRxiv. 2020 Jun 23; doi: 10.1101/2020.05.29.20086645.

Characteristics and Outcomes of COVID-19 Patients in New York City's Public Hospital System.

medRxiv : the preprint server for health sciences

Roopa Kalyanaraman Marcello, Johanna Dolle, Shelia Grami, Richard Adule, Zeyu Li, Kathleen Tatem, Chinyere Anyaogu, Raji Ayinla, Noella Boma, Terence Brady, Braulio F Cosme-Thormann, Kenra Ford, Kecia Gaither, Marc Kanter, Stuart Kessler, Ross B Kristal, Joseph J Lieber, Vikramjit Mukherjee, Vincent Rizzo, Madden Rowell, David Stevens, Elana Sydney, Andrew Wallach, Dave A Chokshi, Nichola Davis

PMID: 32577680 PMCID: PMC7302285 DOI: 10.1101/2020.05.29.20086645

Abstract

Background New York City (NYC) has borne the greatest burden of COVID-19 in the United States, but information about characteristics and outcomes of racially/ethnically diverse individuals tested and hospitalized for COVID-19 remains limited. In this case series, we describe characteristics and outcomes of patients tested for and hospitalized with COVID-19 in New York City's public hospital system. Methods We reviewed the electronic health records of all patients who received a SARS-CoV-2 test between March 5 and April 9, 2020, with follow up through April 16, 2020. The primary outcomes were a positive test, hospitalization, and death. Demographics and comorbidities were also assessed. Results 22254 patients were tested for SARS-CoV-2. 13442 (61%) were positive; among those, the median age was 52.7 years (interquartile range [IQR] 39.5-64.5), 7481 (56%) were male, 3518 (26%) were Black, and 4593 (34%) were Hispanic. Nearly half (4669, 46%) had at least one chronic disease (27% diabetes, 30% hypertension, and 21% cardiovascular disease). Of those testing positive, 6248 (46%) were hospitalized. The median age was 61.6 years (IQR 49.7-72.9); 3851 (62%) were male, 1950 (31%) were Black, and 2102 (34%) were Hispanic. More than half (3269, 53%) had at least one chronic disease (33% diabetes, 37% hypertension, 24% cardiovascular disease, 11% chronic kidney disease). 1724 (28%) hospitalized patients died. The median age was 71.0 years (IQR 60.0, 80.9); 1087 (63%) were male, 506 (29%) were Black, and 528 (31%) were Hispanic. Chronic diseases were common (35% diabetes, 37% hypertension, 28% cardiovascular disease, 15% chronic kidney disease). Male sex, older age, diabetes, cardiac history, and chronic kidney disease were significantly associated with testing positive, hospitalization, and death. Racial/ethnic disparities were observed across all outcomes. Conclusions and Relevance This is the largest and most racially/ethnically diverse case series of patients tested and hospitalized for COVID-19 in the United States to date. Our findings highlight disparities in outcomes that can inform prevention and testing recommendations.

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