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J Funct Biomater. 2020 Jun 22;11(2). doi: 10.3390/jfb11020044.

Time-Transient Effects of Silver and Copper in the Porous Titanium Dioxide Layer on Antibacterial Properties.

Journal of functional biomaterials

Masaya Shimabukuro, Akari Hiji, Tomoyo Manaka, Kosuke Nozaki, Peng Chen, Maki Ashida, Yusuke Tsutsumi, Akiko Nagai, Takao Hanawa

Affiliations

  1. Department of Biomaterials, Faculty of Dental Science, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
  2. Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan.
  3. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
  4. Research Center for Structural Materials, National Institute for Materials Science (NIMS), 1-2-1 Sengen, Tsukuba, Ibaraki 305-0047, Japan.
  5. Department of Anatomy, School of Dentistry, Aichi Gakuin University, 1-100 Kusumoto, Chikusa-ku, Nagoya 464-8650, Japan.

PMID: 32580288 PMCID: PMC7353535 DOI: 10.3390/jfb11020044

Abstract

Recently, silver (Ag) and copper (Cu) have been incorporated into a titanium (Ti) surface to realize their antibacterial property. This study investigated both the durability of the antibacterial effect and the surface change of the Ag- and Cu-incorporated porous titanium dioxide (TiO

Keywords: antibacterial; biofilm; coatings; copper; implant; silver; surface modification

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