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Pathogens. 2020 Jun 30;9(7). doi: 10.3390/pathogens9070527.

Hepatic Stellate Cells and Hepatocytes as Liver Antigen-Presenting Cells during .

Pathogens (Basel, Switzerland)

Paula Constanza Arriola Benitez, Ayelén Ivana Pesce Viglietti, María Mercedes Elizalde, Guillermo Hernán Giambartolomei, Jorge Fabián Quarleri, María Victoria Delpino, Leinhardt

Affiliations

  1. Instituto de Inmunología, Genética y Metabolismo (INIGEM), Universidad de Buenos Aires, CONICET, Buenos Aires 1120, Argentina.
  2. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS), Universidad de Buenos Aires, CONICET, Buenos Aires 1121, Argentina.

PMID: 32629846 PMCID: PMC7399813 DOI: 10.3390/pathogens9070527

Abstract

In Brucellosis, the role of hepatic stellate cells (HSCs) in the induction of liver fibrosis has been elucidated recently. Here, we study how the infection modulates the antigen-presenting capacity of LX-2 cells.

Keywords: Brucella; HSC; IL-10; MHC

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