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Mansukhani K, Dhonde M, Sreenivasan A, et al. Sural Radial Amplitude Ratio: A Study in Healthy Indian Subjects. Ann Indian Acad Neurol. 2020;23(3):255-260doi: 10.4103/aian.AIAN_321_20.
Mansukhani, K., Dhonde, M., Sreenivasan, A., Sharma, A., Balakrishnan, L., & Chavan, P. (2020). Sural Radial Amplitude Ratio: A Study in Healthy Indian Subjects. Annals of Indian Academy of Neurology, 23(3), 255-260. https://doi.org/10.4103/aian.AIAN_321_20
Mansukhani, Khushnuma, et al. "Sural Radial Amplitude Ratio: A Study in Healthy Indian Subjects." Annals of Indian Academy of Neurology vol. 23,3 (2020): 255-260. doi: https://doi.org/10.4103/aian.AIAN_321_20
Mansukhani K, Dhonde M, Sreenivasan A, Sharma A, Balakrishnan L, Chavan P. Sural Radial Amplitude Ratio: A Study in Healthy Indian Subjects. Ann Indian Acad Neurol. 2020 May-Jun;23(3):255-260. doi: 10.4103/aian.AIAN_321_20. Epub 2020 Jun 05. PMID: 32606508; PMCID: PMC7313579.
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Ann Indian Acad Neurol. 2020 May-Jun;23(3):255-260. doi: 10.4103/aian.AIAN_321_20. Epub 2020 Jun 05.

Sural Radial Amplitude Ratio: A Study in Healthy Indian Subjects.

Annals of Indian Academy of Neurology

Khushnuma Mansukhani, Mayura Dhonde, Aarthika Sreenivasan, Alika Sharma, Lajita Balakrishnan, Priyanka Chavan

Affiliations

  1. Clinical Neurophysiology, Bombay Hospital, Mumbai, India.
  2. Neuro-Electrophysiologist, Dhonde Hospital, Nanded, India.
  3. Neurophysiologist CNS Clinic, Navi Mumbai, India.
  4. Associate Consultant, Bombay Hospital, Mumbai, India.
  5. Neurophysiologist, Apollo Hospital, Navi Mumbai, India.
  6. Junior Consultant, Bombay Hospital, Mumbai, Maharashtra, India.

PMID: 32606508 PMCID: PMC7313579 DOI: 10.4103/aian.AIAN_321_20

Abstract

CONTEXT: The amplitude ratio of sural radial sensory nerve action potential is used as a sensitive measure for the diagnosis of an early distal axonal peripheral neuropathy. There is no age-stratified reference data available.

AIM: To establish age-stratified sural radial amplitude ratio (SRAR) reference data in healthy Indian subjects.

STUDY SETTING AND DESIGN: The study was conducted in the electrodiagnostic laboratory of a tertiary city hospital and is an analytical, prospective, and field trial study.

MATERIALS AND METHODS: A prospective study was conducted on 146 healthy volunteers between 18 and 86 years, stratified into 6 groups, a = 18-30 years, b = 31-40 years, c = 41-50 years, d = 51-60 years, e = 61-70 years, and f = >70 years.

SURAL: Radial amplitude ratio was calculated.

STATISTICAL METHODS: Stata 12.1 statistical program was used. Lower limit of SRAR was obtained (mean-2SD of transformed data). ANOVA defined the intergroup variability, and linear regression and Pearson's correlation assessed the statistical significance.

RESULTS: The lower limit of normal SRAR, for each age group is as follows: a: 0.30, b: 0.23, c: 0.20, d: 0.17, e: 0.17, and f: 0.08. SRAR of groups a, b, c was significantly different from groups e and f. Similarly, SRAR was significantly different between groups d and

CONCLUSION: This study provides age-stratified reference data for SRAR. There is evidence to suggest that SRAR varies with age; hence, a single value of SRAR should not be used when diagnosing a peripheral neuropathy based on this criterion.

Copyright: © 2006 - 2020 Annals of Indian Academy of Neurology.

Keywords: Age-stratified; Indian population; SRAR; reference data

Conflict of interest statement

There are no conflicts of interest.

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