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Inoue M, Matsumoto M, Sakuhara Y, et al. Acute progressing hepatic angiosarcoma: An autopsy case report. Radiol Case Rep. 2020;15(8):1403-1407doi: 10.1016/j.radcr.2020.06.003.
Inoue, M., Matsumoto, M., Sakuhara, Y., Takakuwa, Y., Yoshii, S., Akakura, N., & Sakamoto, N. (2020). Acute progressing hepatic angiosarcoma: An autopsy case report. Radiology case reports, 15(8), 1403-1407. https://doi.org/10.1016/j.radcr.2020.06.003
Inoue, Masaki, et al. "Acute progressing hepatic angiosarcoma: An autopsy case report." Radiology case reports vol. 15,8 (2020): 1403-1407. doi: https://doi.org/10.1016/j.radcr.2020.06.003
Inoue M, Matsumoto M, Sakuhara Y, Takakuwa Y, Yoshii S, Akakura N, Sakamoto N. Acute progressing hepatic angiosarcoma: An autopsy case report. Radiol Case Rep. 2020 Jun 29;15(8):1403-1407. doi: 10.1016/j.radcr.2020.06.003. eCollection 2020 Aug. PMID: 32636983; PMCID: PMC7329938.
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Radiol Case Rep. 2020 Jun 29;15(8):1403-1407. doi: 10.1016/j.radcr.2020.06.003. eCollection 2020 Aug.

Acute progressing hepatic angiosarcoma: An autopsy case report.

Radiology case reports

Masaki Inoue, Mio Matsumoto, Yusuke Sakuhara, Yasunari Takakuwa, Shinji Yoshii, Nobuaki Akakura, Naoya Sakamoto

Affiliations

  1. Department of Gastroenterology, Sapporo Medical Center NTT EC, Minami 1-jo nishi 15-chome Chuo-ku, Sapporo 060-0061, Japan.
  2. Department of Diagnostic Radiology, Tonan Hospital, kita 4-jo nishi 7-chome 3-8 chuo-ku, Sapporo 060-0004, Japan.
  3. Department of Surgical Pathology, Sapporo Medical Center NTT EC, Minami 1-jo nishi 15-chome Chuo-ku, Sapporo 060-0061, Japan.
  4. Department of Gastroenterology and Hepatology, Graduate school of Medicine, Hokkaido University, kita 14-jo nishi 5-chome kita-ku, Sapporo 060-8648, Japan.

PMID: 32636983 PMCID: PMC7329938 DOI: 10.1016/j.radcr.2020.06.003

Abstract

A man in his 50s presented with pitting edema of both lower legs and abdominal distension as his chief complaint. His personal medical history and family history were unremarkable, except that he was a heavy drinker consuming 66 g of alcohol per day and a heavy smoker. Blood tests upon admission showed slight hepatic dysfunction, thrombocytopenia, jaundice, hypoalbuminemia, and decreased coagulability. Tumor marker tests showed elevated levels of CA19-9 and PIVKA-II. Contrast-enhanced computed tomography revealed enhancement of multiple masses predominantly in the right lobe of the liver in the early phase, followed by diffuse enhancement of the entire liver in the delayed phase. Hepatic arteriography demonstrated large hemangioma-like lesions corresponding to the masses revealed by computed tomography. That findings seemed to be cotton wool appearance. On magnetic resonance images, there were multiple mass-like lesions that showed homogeneous or heterogeneous low signal intensity on T1-weighted images, and clearly high signal intensity on T2-weighted images. The findings were atypical and no definite diagnosis could be made. Hepatic failure then rapidly worsened, and the patient died on hospital day 20. Autopsy led to the diagnosis of hepatic angiosarcoma.

© 2020 The Authors. Published by Elsevier Inc. on behalf of University of Washington.

Keywords: Hepatic angiosarcoma; Hepatic hemangioma; Hepatic tumor

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