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Hutt E, Vajapey R, Van Iterson EH, et al. Functional capacity and quality of life in the postural tachycardia syndrome: A retrospective cross-sectional study. Ann Med Surg (Lond). 2020;56:72-76doi: 10.1016/j.amsu.2020.06.013.
Hutt, E., Vajapey, R., Van Iterson, E. H., Jaeger, F., Cho, L., Ahmed, H. M., & Mayuga, K. A. (2020). Functional capacity and quality of life in the postural tachycardia syndrome: A retrospective cross-sectional study. Annals of medicine and surgery (2012), 5672-76. https://doi.org/10.1016/j.amsu.2020.06.013
Hutt, Erika, et al. "Functional capacity and quality of life in the postural tachycardia syndrome: A retrospective cross-sectional study." Annals of medicine and surgery (2012) vol. 56 (2020): 72-76. doi: https://doi.org/10.1016/j.amsu.2020.06.013
Hutt E, Vajapey R, Van Iterson EH, Jaeger F, Cho L, Ahmed HM, Mayuga KA. Functional capacity and quality of life in the postural tachycardia syndrome: A retrospective cross-sectional study. Ann Med Surg (Lond). 2020 Jun 12;56:72-76. doi: 10.1016/j.amsu.2020.06.013. eCollection 2020 Aug. PMID: 32612820; PMCID: PMC7322180.
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Ann Med Surg (Lond). 2020 Jun 12;56:72-76. doi: 10.1016/j.amsu.2020.06.013. eCollection 2020 Aug.

Functional capacity and quality of life in the postural tachycardia syndrome: A retrospective cross-sectional study.

Annals of medicine and surgery (2012)

Erika Hutt, Ramya Vajapey, Erik H Van Iterson, Fredrick Jaeger, Leslie Cho, Haitham M Ahmed, Kenneth A Mayuga

Affiliations

  1. Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH, USA.

PMID: 32612820 PMCID: PMC7322180 DOI: 10.1016/j.amsu.2020.06.013

Abstract

BACKGROUND: Postural tachycardia syndrome (POTS) is a complex syndrome of orthostatic intolerance that significantly affects quality of life. The relationship between functional capacity, quality of life, and age remains poorly understood in this patient population. The purpose of this cross-sectional study was to assess the clinical and exercise characteristics of patients with POTS who underwent exercise stress testing as part of cardiac rehabilitation, and to evaluate the relationships between functional capacity with age and sex, as well as the relationship between functional capacity and quality of life.

METHODS: We included 255 consecutive adult patients with the diagnosis of POTS, by tilt table testing, who underwent exercise stress testing between 2012 and 2017. Clinical and stress test data were obtained from electronic medical records.

RESULTS: Of the 255 patients, 232 (91%) were women, with median age 33.5 years. Prevalence of traditional CAD risk factors was low (2% diabetes, 13% hypertension, 7% hyperlipidemia, and 26% smoking history). Mean resting BP was 114 ± 13 mmHg systolic, resting HR was 76 ± 13 bpm, METs achieved 9.2 ± 2.2, and 1 min HR recovery 32 ± 17 bpm. 113 patients (44%) had abnormal functional capacity for age and sex. When analyzed by age groups, younger POTS patients had increasingly lower than expected functional capacity (compared to predicted normals) than did older patients (ANOVA

CONCLUSIONS: In this large cohort, patients with POTS were predominantly female (91%) and relatively young. The novel findings are that younger patients with POTS were more likely to have lower-than-average functional capacity for their age and sex compared to older patients, and that abnormal functional capacity was associated with lower quality of life by SF-36 physical component.

© 2020 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.

Keywords: Age; Functional capacity; Gender; Postural tachycardia syndrome; Quality of life

Conflict of interest statement

Nothing to declare.

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