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Hurtado M, Prokai L, Sankpal UT, et al. Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells. Process Biochem. 2019;89:155-164doi: 10.1016/j.procbio.2019.10.022.
Hurtado, M., Prokai, L., Sankpal, U. T., Levesque, B., Maram, R., Chhabra, J., Brown, D. T., Gurung, R. K., Holder, A. A., Vishwanatha, J. K., & Basha, R. (2020). Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells. Process biochemistry (Barking, London, England), 89155-164. https://doi.org/10.1016/j.procbio.2019.10.022
Hurtado, Myrna, et al. "Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells." Process biochemistry (Barking, London, England) vol. 89 (2020): 155-164. doi: https://doi.org/10.1016/j.procbio.2019.10.022
Hurtado M, Prokai L, Sankpal UT, Levesque B, Maram R, Chhabra J, Brown DT, Gurung RK, Holder AA, Vishwanatha JK, Basha R. Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells. Process Biochem. 2020 Feb;89:155-164. doi: 10.1016/j.procbio.2019.10.022. Epub 2019 Oct 30. PMID: 32719579; PMCID: PMC7384693.
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Process Biochem. 2020 Feb;89:155-164. doi: 10.1016/j.procbio.2019.10.022. Epub 2019 Oct 30.

Next generation sequencing and functional pathway analysis to understand the mechanism of action of copper-tolfenamic acid against pancreatic cancer cells.

Process biochemistry (Barking, London, England)

Myrna Hurtado, Laszlo Prokai, Umesh T Sankpal, Blair Levesque, Rajasekhar Maram, Jaya Chhabra, Deondra T Brown, Raj K Gurung, Alvin A Holder, Jamboor K Vishwanatha, Riyaz Basha

Affiliations

  1. Biochemistry and Cancer Biology, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, 76107, United States.
  2. Department of Pharmacology and Neuroscience, Institute for Healthy Aging, Graduate School of Biomedical Sciences, University of North Texas Health Science Center, Fort Worth, TX, 76107, United States.
  3. Texas College of Osteopathic Medicine, University of North Texas Health Science Center, Fort Worth, TX, 76107, United States.
  4. Department of Chemistry and Biochemistry, Old Dominion University, Norfolk, VA, 23529, United States.
  5. Department of Microbiology, Immunology and Genetics, Graduate School of Biomedical Sciences University of North Texas Health Science Center, Fort Worth, TX, 76107, United States.

PMID: 32719579 PMCID: PMC7384693 DOI: 10.1016/j.procbio.2019.10.022

Abstract

Anti-cancer activity of tolfenamic acid (TA) in preclinical models for pancreatic cancer (PaCa) is well established. Since the dosage for anti-cancer actions of TA is rather high, we recently demonstrated that IC

Keywords: Apoptosis; Copper-tolfenamic acid; Gene expression; Next generation sequencing; Pancreatic cancer; Pathway analysis

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