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Wang J, Wang SY, Zhu XN, et al. [Efficacy of Oral Corticosteroids in Preventing Esophageal Stenosis after Large Area Endoscopic Submucosal Tunnel Dissection]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2018;49(6):845-848
Wang, J., Wang, S. Y., Zhu, X. N., Wu, J. C., Yang, J. L., & Gan, T. (2018). [Efficacy of Oral Corticosteroids in Preventing Esophageal Stenosis after Large Area Endoscopic Submucosal Tunnel Dissection]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 49(6), 845-848.
Wang, Jin, et al. "[Efficacy of Oral Corticosteroids in Preventing Esophageal Stenosis after Large Area Endoscopic Submucosal Tunnel Dissection]." Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition vol. 49,6 (2018): 845-848.
Wang J, Wang SY, Zhu XN, Wu JC, Yang JL, Gan T. [Efficacy of Oral Corticosteroids in Preventing Esophageal Stenosis after Large Area Endoscopic Submucosal Tunnel Dissection]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Nov;49(6):845-848. Chinese. PMID: 32677390.
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Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Nov;49(6):845-848.

[Efficacy of Oral Corticosteroids in Preventing Esophageal Stenosis after Large Area Endoscopic Submucosal Tunnel Dissection].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

[Article in Chinese]
Jin Wang, Shu-Yan Wang, Xiao-Nan Zhu, Jun-Chao Wu, Jin-Lin Yang, Tao Gan

Affiliations

  1. Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, China.

PMID: 32677390

Abstract

OBJECTIVE: To evaluate the efficacy of oral corticosteroids in preventing esophageal stenosis after large area esophageal endoscopic submucosal tunnel dissection (ESTD).

METHODS: The patients undertook esophageal ESTD were included from January 2014 to January 2018. The inclusion criteria was single lesion of esophageal early esophagus cancer with the extent more than 3/4 of circumferential degree. According to the inclusion time, the patients were divided into the trial group (ESTD + oral corticosteroids) and the control group (simple ESTD). The incidence of the total esophageal stenosis, intractable esophageal stenosis, the remission rate of dysphagia and the period from the dysphagia present were observed and compared in the two groups.

RESULTS: A total of 101 cases of esophageal ESTD patients were included. There were 48 cases in the trial group, 28 cases of male and 20 cases of female, with an average age of (62.98±7.52) years; 53 cases in the control group, 28 cases of male and 25 cases of female, with an average age of (62.67±8.04) years. The rate of intractable esophageal stenosis in the trial group was lower than that in the control group (6.25% vs. 20.75%,

CONCLUSIONS: Oral corticosteroids can effectively reduce the degree of esophageal stenosis after large area ESTD, as well as the incidence of intractable esophageal stenosis and the number of endoscopic treatment in non-refractory esophageal stenosis patients.

Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).

Keywords: Corticosteroids; Early esophageal cancer; Endoscopic submucosal dissection; Esophageal stenosis

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