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Sichuan Da Xue Xue Bao Yi Xue Ban. 2018 Nov;49(6):920-923.

[Clinical Research on the Post-operative Hemodynamics Changes in Donors after Living Donor Liver Transplantation].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition

[Article in Chinese]
Qing Wang, Yi-Ding Fan, Lü-Nan Yan, Hai-Qing Wang, Yu-Cheng Ma, Ming Li, Huai-Rong Tang

Affiliations

  1. Department of Hepatic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
  2. Department of Operations Management, West China Hospital, Sichuan University, Chengdu 610041, China.
  3. Department of Health Center, West China Hospital, Sichuan University, Chengdu 610041, China.

PMID: 32677405

Abstract

OBJECTIVE: To investigate the postoperative hemodynamics changes and their influence factors in the donors after right lobe living donor liver transplantation.

METHODS: A total of 53 consecutive living donors from Dec 2010 to Aug 2015 who underwent donor right lobe hepatectomy were retrospectively analyzed. We measured residual liver hemodynamics with color doppler ultrasound, detected liver stiffness by transient elastography, also analyzed postoperative liver function, hemodynamics, and the long term variation tendency of hepatocirrhosis and spleen.

RESULTS: One week after operation, transient liver damage was observed. Post-operative hemodynamics within the follow-up time showed:portal vein diameter was gradually increasing, the velocity decreased gradually;Hepatic vein diameter increased, and the velocity decreased gradually. There was a negative correlation between portal vein diameter and portal vein velocity (

CONCLUSIONS: The donor presented a transient liver injury after operation, but tended to be recovery after one week. Despite post-operative hemodynamic undergo a series of changes, but it does not affect the post-operative long-term donor safety.

Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).

Keywords: Donors; Hemodynamics; Living donor liver transplantation

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